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Mechanisms of Cocaine Abuse and Toxicity |
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NIDA Research Monograph, Number 88 [Printed in 1988]This monograph is not available by chapter. The Table of Contents (below) is shown to assist in locating information prior to downloading the monograph.Download Monograph88.pdf - Mechanisms of Cocaine Abuse and Toxicity (2.6 MB) Table of Contents Foreword-----ix Pharmacological Effects of Cocaine Relevant to Its Abuse-----1 Cocaine-Reinforced Behavior-----14 Cocaine Receptors on Monoamine Transporters and Sodium Channels-----23 Modulation of Cocaine Receptors-----44 Sensitization to Cocaine in the Nigrostriatal Dopamine System-----55 The Interaction of Cocaine With Central Serotonergic Neuronal Systems: Cellular Electrophysiologic Approaches-----78 The Effects of Cocaine on Local Cerebral Metabolic Activity-----92 Behavioral Studies of the Reinforcing Properties of Cocaine-----107 Pharmacological Modifications of Cocaine and Opioid Self-Administration-----125 Reinforcement Pathways for Cocaine-----137 Multiple Dopamine Receptors and the Behavioral Effects of Cocaine-----160 Neurobehavioral Pharmacology of Cocaine-----185 Intracranial Cocaine Self-Administration-----199 Psychomotor Stimulant vs. Local Anesthetic Effects of Cocaine: Role of Behavioral Sensitization and Kindling-----217 Genetic Differences in Responses to Cocaine-----239 Hepatotoxicity of Cocaine-----250 Lack of Toxic Effects of Cocaine on Dopamine or Serotonin Neurons in the Rat Brain-----276 Developmental Effects of Cocaine-----290 Cardiovascular Toxicity of Cocaine-----304 Arteriosclerotic Toxicity of Cocaine-----325 Mechanisms of Cocaine Abuse and Toxicity: An Overview-----337 List of NIDA Research Monographs-----354 |
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