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Opioid Peptides: An Update |
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![]() NIDA Research Monograph, Number 87 [Printed in 1988]![]() Download Monograph87.pdf - Opioid Peptides: An Update (2.9 MB) Table of Contents Preface-----v Neuropeptides, A Personalized History-----1 Synthesis and Biological Activity of Novel Met-enkephalin Analogs-----10 Approaches to Studying Structure-Activity Relationships in Peptide Hormones Through the Expression of Synthetic Genes-----20 X-Ray Diffraction Studies of Enkephalins and Opiates-----41 Conformational Analysis of Cyclic Opioid Peptide Analogs-----60 Conformational Studies of Dermorphin-----74 Use of Molecular Biological Methods to Study Neuropeptides-----83 Three Technical Approaches for Cloning Opioid Receptors-----93 Effects of Opioid Peptides on Human Neuroblastoma Cells-----111 Analgesia and Neuropeptides-----118 Mechanism of Development of Tolerance and Dependence to Opioids in Neuroblastoma x Glioma Hybrid Cells and Mice-----157 Development of Spinal Substrate for Nociception in Man-----167 Differential Effects of Opioid Peptides Administered Intracerebrally in Loci of Self-Stimulation Reward of Lateral Hypothalamus and Ventral Tegmental Area-Substantia Nigra-----180 Peptides and Thermoregulation-----192 Endogenous Opioids and Immune Responses: An Experimental Study-----209 An Update of Selected Topics in the Biology and Chemistry of Opioid Peptides-----217 List of NIDA Research Monographs-----233 |
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