NIDA Research Monograph, Number 60 [Printed in 1985]
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Download Monograph60.pdf - Prenatal Drug Exposure: Kinetics and Dynamics (1.1 MB)
Table of Contents
Introduction and Overview-----1
C. Nora Chiang and Charles C. Lee
Animal Models for Study of Fetal Drug Exposure-----5
Abraham M. Rudolph
Biotransformation of Drugs and Foreign Chemicals in the Human
Fetal-Placental Unit-----17
M.R.Juchau
Pharmacokinetics of Drugs and Metabolites in the Maternal-Placental-Fetal Unit: General Principles-----25
Laurene H. Wang, Abraham M. Rudolph, and Leslie Z. Benet
The Pharmacodynamics of Prenatal Chemical Exposure-----39
Richard K. Miller and Carol K. Kellogg
Opioids and Development: New Lessons From Old Problems-----58
Ian S. Zagon
Pharmacodynamics of Fetal Exposure to Narcotics-----78
Hazel H. Szeto and Jason G. Umans
Positron-Emission Tomography: A New Approach to Feto-Maternal Pharmacokinetics-----88
Bo S. Lindberg, Per Hartvig, Anders Lilja, Hans Lundqvist. Bengt Langstrom, Petter Malmborg, Anders Rane, Annika Rimland, and Hans Svard
Placental Transfer of Drugs, Alcohol, and Components of Cigarette Smoke and Their Effects on the Human Fetus-----98
Betty R. Kuhnert and Paul M. Kuhnert
Appendix--Maternal-Fetal Transfer of Abused Substances: Pharmacokinetic and Pharmacodynamic Data-----110
Charles C. Lee and C. Nora Chiang
List of NIDA Research Monographs-----148
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