NIDA Research Monograph, Number 114 [Printed in 1991]
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Download Monograph114.pdf - Methodological Issues in Controlled Studies on Effects of Prenatal Exposure to Drug Abuse (1.5 MB)
Table of Contents
Preface-----vii
M. Madyne Kilbey and Khursheed Asghar
Session: Detection and Quantification of Prenatal Drug Exposure in Infants
Drug Exposure to the Fetus-The Effect of Smoking-----1
Betty R. Kuhnert
Pharmacokinetic Correlates of Fetal Drug Exposure-----18
C. Lindsay DeVane
Discussion: Methodological Issues in Controlled Studies on Effects
of Prenatal Drugs-----37
Hazel H. Szeto
Session: Assessment of Pregnancy Outcome
Selected Methodologic Issues in Investigations of Prenatal Effects
of Cocaine: Lessons From the Past-----45
Barry Zuckerman
Methodological Issues in Studying Cocaine Use in Pregnancy:
A Problem of Definitions-----55
lra J. Chasnoff
Use of Birth Defects Monitoring Programs for Assessing the Effects
of Maternal Substance Abuse on Pregnancy Outcomes-----66
M. Louise Martin and Larry D. Edmonds
Discussion: Methodologic Issues in Assessment of
Pregnancy Outcomes-----84
Ronald A. Chez
Session: Assessment of Status of the Newborn
What We Can Learn From the Status of the Newborn-----93
T. Berry Brazelton
Neurobehavioral Organization of the Newborn:
Opportunity for Assessment and Intervention-----106
Heidelise Als
Substance Abuse in Pregnancy: Effects on Cardiorespiratory
Function in the Infant-----117
Eduardo Bancalari
The Effect of Cocaine on Developing HumanBrain-----128
Barry E. Kosofsky
Discussion: Assessing Status of the Newborn-----144
Edward Z. Tronick
Session: Measurement of Drug-Induced Physical and
Behavioral Delays and/or Abnormalities: A General Framework
Measurement of Drug-Induced Physical and Behavioral Delays and
Abnormalities in Animal Studies: A General Framework-----148
Sheldon B. Sparber
Regulatory Disorders I: Clinical Perspectives-----165
Stanley I. Greenspan
Regulatory Disorders II: Psychophysiologic Perspectives-----173
Stephen W. Porges and Stanley I. Greenspan
Discussion: Measurement of Drug-Induced Physical and Behavioral
Delays and Abnormalities-A General Framework-----182
Joseph L. Jacobson
Session: Measurement of Drug-Induced Physical and
Behavioral Delays and/or Abnormalities: (A) Physiology
and (B) Neuroendocrinology
Postnatal Development of Cardiac and Respiratory Control
Following Prenatal Drug Exposure-----187
Ronald M. Harper
Endocrine Function as a Target of Perinatal Drug
Effects: Methodologic Issues-----206
Cynthia Kuhn, Diane Ignar, and Rolf Windh
Discussion: Neuroteratology of Cocaine Relationship
to Developing Monoamine Systems-----233
Jean M. Lauder
Session: Measurement of Drug-Induced Physical and
Behavioral Delays and/or Abnormalities: (C) Learning
and Cognition and (D) Social Bonding/Emotional
and Development
Assessment of Teratogenic Effects on Cognitive and
Behavioral Development in Infancy and Childhood-----248
Joseph L. Jacobson and Sandra W. Jacobson
New Methodologies for Evaluating Residual Brain Damage In
Infants Exposed to Drugs of Abuse: Objective Methods for
Describing Movements, Facial Expressions, and
Communicative Behaviors-----262
Edward Z. Tronick, Marjorie Beeghly, Linda Fetters,
and M. Katherine Weinberg
Rationale and Methodologies for Developing Nonhuman
Primate Models of Prenatal Drug Exposure-----291
Stephen J. Suomi and J. Dee Higley
Discussion: Measurement of Drug-Induced Delays in Learning
and Cognition and Social and Emotional Development-----303
Sheldon B. Sparber
Session: Tracking Drug Effects Over the Lifespan
Following Drug-Exposed Infants Into Middle Childhood:
Challenges to Researchers-----310
Sydney L. Hans
Patterns of Growth and Development in Narcotic-Exposed Children-----323
Marta H. Lifschitz and Geraldine S. Wilson
Integrity of Psychopathology Diagnoses Across the Lifespan-----340
Patricia Cohen and Judith S. Brook
Discussion: Drug Effects-A Search for Mechanisms-----352
Barry Zuckerman
List of NIDA Research Monographs-----363
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