GnRH Agonist and Intrauterine Insemination

This study has been completed.

First Received: July 17, 2007 Last Updated: June 30, 2008 History of Changes

Sponsored by:	Instituto Valenciano de Infertilidad, Spain
Information provided by:	Instituto Valenciano de Infertilidad, Spain
ClinicalTrials.gov Identifier:	NCT00503217

Purpose

The aim of this study is to assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles.

Condition	Intervention	Phase
Intrauterine Insemination	Drug: Tryptorelin	Phase IV

Study Type:	Interventional
Study Design:	Randomized, Single Blind, Placebo Control, Parallel Assignment, Efficacy Study
Official Title:	Effect of GnRH Agonist Administration at the Time of Implantation in Intrauterine Insemination Cycles: A Randomized Controlled Trial

Resource links provided by NLM:

Drug Information available for: Gonadorelin Gonadorelin hydrochloride LH-RH

U.S. FDA Resources

Eligibility

Ages Eligible for Study:	18 Years to 38 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Women < 38 years old
Bilateral tubal patency confirmed by hysterosonography
Normal ultrasound scan of uterus and ovaries
Normal day 3 basal hormones
Motile sperm count after capacitation ≥ 3 mill/ml

Exclusion Criteria:

Endometriosis
Polycystic ovary syndrome
Uterine disease (polyps, myomas and müllerian diseases)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00503217

Locations

Spain
Instituto Valenciano de Infertilidad Spain
Valencia, Spain, 46015

Sponsors and Collaborators

Instituto Valenciano de Infertilidad, Spain

Investigators

Principal Investigator:	Jose Bellver, MD	Instituto Valenciano de la Infertilidad
Principal Investigator:	Elena Labarta, MD	Instituto Valenciano de Infertilidad

More Information

No publications provided

Study ID Numbers:	VLC-JB-0205-307-9
Study First Received:	July 17, 2007
Last Updated:	June 30, 2008
ClinicalTrials.gov Identifier:	NCT00503217 History of Changes
Health Authority:	Spain: Ministry of Health

Keywords provided by Instituto Valenciano de Infertilidad, Spain:

intrauterine insemination
GnRH agonist
implantation

Study placed in the following topic categories:

Deslorelin

Additional relevant MeSH terms:

Deslorelin
Molecular Mechanisms of Pharmacological Action
Enzyme Inhibitors
Pharmacologic Actions

ClinicalTrials.gov processed this record on September 11, 2009