Does Undercorrection of Myopia Retard Myopia Progression Among Kindergarten Children?

This study is currently recruiting participants.

Verified by KK Women's and Children's Hospital, March 2005

First Received: July 3, 2006 Last Updated: November 15, 2006 History of Changes

Sponsored by:	KK Women's and Children's Hospital
Information provided by:	KK Women's and Children's Hospital
ClinicalTrials.gov Identifier:	NCT00348166

Purpose

The purpose of this study is to find out if undercorrection of myopia slow down the progression of myopia in kindergarten children.

Condition	Intervention	Phase
Refractive Error - Myopia	Drug: cyclopentolate	Phase I

Study Type:	Interventional
Study Design:	Randomized, Double-Blind, Active Control, Factorial Assignment
Official Title:	Does Undercorrection of Myopia Retard Myopia Progression Among Kindergarten

Resource links provided by NLM:

MedlinePlus related topics: Refractive Errors

Drug Information available for: Cyclopentolate Cyclopentolate hydrochloride

U.S. FDA Resources

Further study details as provided by KK Women's and Children's Hospital:

Estimated Enrollment:	180
Study Start Date:	December 2005

Eligibility

Ages Eligible for Study:	5 Years to 6 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Children of chinese descent aged 5 - 6yrs
Refractive error of -1.00 to -3.00Ds
Less than 1.50 astigmatism in each eye. (No oblique axis)
Visual acuity is 6/6 or better in both eyes.
No binocular problems, no anisometropia >1.50D
Will be staying in S'pore for at least 2 years.

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00348166

Locations

Singapore
KK Women's and Children's Hospital	Recruiting
100 Bukit Timah Road, Singapore, 229899
Contact: Huang Yaxin Shareen +6598182512 ext 8710 shareenhuang@hotmail.com
Principal Investigator: Huang Yaxin Shareen

Sponsors and Collaborators

KK Women's and Children's Hospital

Investigators

Principal Investigator:

Quah Boon Long

Singapore National Eye Centre

More Information

No publications provided

Study ID Numbers:	RAU/085/2005
Study First Received:	July 3, 2006
Last Updated:	November 15, 2006
ClinicalTrials.gov Identifier:	NCT00348166 History of Changes
Health Authority:	Singapore: Domain Specific Review Boards

Study placed in the following topic categories:

Muscarinic Antagonists
Neurotransmitter Agents
Mydriatics
Cholinergic Antagonists
Eye Diseases
Disease Progression

Peripheral Nervous System Agents
Myopia
Cholinergic Agents
Cyclopentolate
Refractive Errors

Additional relevant MeSH terms:

Parasympatholytics
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Cholinergic Antagonists
Eye Diseases
Physiological Effects of Drugs
Myopia
Cholinergic Agents

Cyclopentolate
Pharmacologic Actions
Muscarinic Antagonists
Mydriatics
Autonomic Agents
Peripheral Nervous System Agents
Refractive Errors

ClinicalTrials.gov processed this record on September 11, 2009