Inclusion Criteria:

• Participants will be approximately 950 adult survivors who are long-term childhood cancer survivors.
• They have to have been smoking for at least one yea.
• The primary inclusionary criterion is that they are a childhood cancer survivor defined as diagnosis of cancer before the age of 21.
• Participants must be at least 18 years of age, and must be at least one year out of active cancer treatment.
• Any histologic subtype of childhood cancer will qualify for entry into this study.
• Participants must speak English and have access to a telephone for participation.

Exclusion Criteria:

• Inability to understand consent procedures
• Current substance abuse or alcohol use of ≥ 21 drinks/week
• Participants with a known contraindication or sensitivity to nicotine replacement therapy may participate in this study; however they will not receive nicotine replacement therapy (NRT) as part of their smoking cessation program.
• Since our participants are childhood cancer survivors and they can be medically fragile and we are interested in providing all eligible participants with NRT to enhance their ability to quit smoking, we added a cautionary conditions list to the recruitment screening form. Those with severe arrhythmias, myocardial infarction, unstable angina, cerebrovascular incident, blood vessel disease, phaeochromocytoma, diabetes, hyperthyroidism, abnormal kidney or liver function, or history of gastritis or peptic ulcers, or who smoke less than 5 cigarettes per day will not receive NRT.
• Patients with questionable NRT eligibility will be discussed/reviewed on a case by case basis with the Staff Family Physician