In Vitro Maturation of Immature Oocytes

This study has been completed.

First Received: May 29, 2007 Last Updated: December 16, 2008 History of Changes

Sponsored by:	Sheba Medical Center
Information provided by:	Sheba Medical Center
ClinicalTrials.gov Identifier:	NCT00480337

Purpose

The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro.

These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as performed during normal IVF.We will record the efficacy and safety of this procedure.

Condition	Intervention
Polycystic Ovary Syndrome Ovarian Hyperstimulation Syndrome	Procedure: In Vitro Maturation of immature oocytes

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment

Eligibility

Ages Eligible for Study:	20 Years to 45 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Women with PCOS
Women with previous Hyperstimulation or with risk of developing hyperstimulation during IVF Treatment
Women diagnosed with cancer who are interested in fertility preservation
Women with repeated IVF failure

Exclusion Criteria:

Severe cases of endometriosis
Large myomas
Hydrosalpinxs Technical problem with previous oocytes pick-up

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00480337

Locations

Israel
IVF Unit, Shea Medical Center, Tel-Hashomer
Ramat-Gan, Israel, 52621

Sponsors and Collaborators

Sheba Medical Center

Investigators

Principal Investigator:

Ariel Hourvitz

IVF Unit, Sheba Medical Center

More Information

No publications provided

Study ID Numbers:	SHEBA-06-4317-AH-CTIL
Study First Received:	May 29, 2007
Last Updated:	December 16, 2008
ClinicalTrials.gov Identifier:	NCT00480337 History of Changes
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Sheba Medical Center:

PCOS
Fertility Preservation
Repeated IVF Failure
S/P Hyperstimulation

Study placed in the following topic categories:

Genital Diseases, Female
Infertility
Gonadal Disorders
Ovarian Hyperstimulation Syndrome
Polycystic Ovary Syndrome
Endocrine System Diseases

Endocrinopathy
Ovarian Diseases
Cysts
Ovarian Cysts
Polycystic Ovarian Syndrome

Additional relevant MeSH terms:

Disease
Gonadal Disorders
Endocrine System Diseases
Ovarian Diseases
Cysts
Adnexal Diseases
Genital Diseases, Female

Neoplasms
Pathologic Processes
Syndrome
Ovarian Hyperstimulation Syndrome
Polycystic Ovary Syndrome
Ovarian Cysts

ClinicalTrials.gov processed this record on September 11, 2009