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| Sponsored by: |
North West London Hospitals NHS Trust |
|---|---|
| Information provided by: | North West London Hospitals NHS Trust |
| ClinicalTrials.gov Identifier: | NCT00307775 |
Purpose
This study will address the following questions:
| Condition | Intervention |
|---|---|
|
Fecal Incontinence |
Drug: oestradiol |
| Study Type: | Interventional |
| Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study |
| Official Title: | A Pilot Study to Examine the Efficacy of Vaginally Administered Oestradiol in the Treatment of Faecal Incontinence in Post Menopausal Women |
| Estimated Enrollment: | 43 |
| Study Start Date: | March 2006 |
| Estimated Study Completion Date: | October 2007 |
Faecal incontinence affects about 5% of women, the most common cause is often cited by women as obstetric trauma.
However in clinical practice many women report that their symptoms of faecal incontinence begin around the same time as menopause. A community survey examining the prevalence of faecal incontinence in menopausal women is in progress. If a correlation is found between the onset of menopause and the development of faecal incontinence, further investigation of effective treatment will be indicated. The investigators want to investigate whether vaginally administered oestradiol can alleviate or improve symptoms in women who have faecal incontinence after the menopause. This is a pilot study.
Eligibility| Ages Eligible for Study: | 45 Years and older |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| United Kingdom | |
| North West London Hospitals NHS Trust | |
| London, United Kingdom, HA1 3UJ | |
| Principal Investigator: | Kathy Abernethy, RN ENB | North West London Hospitals NHS Trust |
| Study Chair: | Joan Pitkin, MB BS BSc FRCS FRCOG | North West London Hospitals NHS Trust |
More Information
| Study ID Numbers: | 06/VO1/6 |
| Study First Received: | March 27, 2006 |
| Last Updated: | February 20, 2007 |
| ClinicalTrials.gov Identifier: | NCT00307775 History of Changes |
| Health Authority: | United Kingdom: National Health Service |
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oestradiol, faecal incontinence, post menopausal post menopausal women with faecal incontinence |
|
Estrogens Fecal Incontinence Contraceptive Agents Benzoates Gastrointestinal Diseases Urination Disorders Hormone Antagonists Estradiol valerate Contraceptive Agents, Female Hormones, Hormone Substitutes, and Hormone Antagonists Estradiol 17 beta-cypionate |
Intestinal Diseases Hormones Rectal Diseases Estradiol Signs and Symptoms Digestive System Diseases Urologic Diseases Estradiol 3-benzoate Urinary Incontinence Polyestradiol phosphate Menopause |
|
Estrogens Fecal Incontinence Contraceptive Agents Gastrointestinal Diseases Urination Disorders Physiological Effects of Drugs Estradiol valerate Contraceptive Agents, Female Hormones, Hormone Substitutes, and Hormone Antagonists Reproductive Control Agents Estradiol 17 beta-cypionate Intestinal Diseases |
Hormones Rectal Diseases Pharmacologic Actions Estradiol Urological Manifestations Signs and Symptoms Digestive System Diseases Urologic Diseases Therapeutic Uses Estradiol 3-benzoate Urinary Incontinence Polyestradiol phosphate |
