[GMPB Membership Roster] [GMPB Meeting Rosters]

The Gastrointestinal Mucosal Pathobiology [GMPB] Study Section reviews applications involving gastrointestinal immunology, host-microbial interactions, intestinal infections, inflammation including inflammatory bowel diseases, and epithelial cell biology as it relates to mucosal defense or repair.  Approaches may utilize in vitro systems, animal models, or research involving human samples and systems.  Emphasis is on basic and translational approaches to mucosal pathophysiology.

Specific areas covered by GMPB include:

• GI mucosal immunology including both innate and adaptive immunity.
• Mechanisms of acute and chronic intestinal inflammation as they relate to pathogenesis. Basic and clinical studies in human inflammatory bowel disease, gluten sensitive enteropathy, auto-immune gastritis, other types of immune-mediated gastrointestinal diseases, necrotizing enterocolitis, and the immune responses to GI infections. Dysplasia and pre-neoplasia as a consequence of chronic GI infection or inflammation (e.g. colitis or H. pylori-induced).
• Interactions between the microbiota and gastrointestinal mucosa including the effects of pathogenic bacteria (including H. pylori, Salmonella and pathogenic E. coli), commensal bacteria, and probiotics.
• Gastrointestinal cell biology and barrier function in health and disease.
• Mechanisms of epithelial injury, repair, regeneration, and adaptation. Regulation of gene expression as it relates to inflammatory and repair processes. Mechanisms of apoptosis and oxidative stress in the GI tract as they relate to inflammatory and repair processes.
  

Study sections with most closely related areas of similar science listed in rank order are:

Clinical, Integrative and Molecular Gastroenterology [CIMG] 
Cancer Etiology [CE]
Hypersensitivity, Autoimmune, and Immune-mediated Diseases [HAI] 
Host Interactions with Bacterial Pathogens [HIBP] 
Immunity and Host Defense [IHD]