Analysis of Human Tear Proteins

This study is currently recruiting participants.

Verified by University of Colorado at Denver and Health Sciences Center, March 2007

First Received: March 26, 2007 Last Updated: March 27, 2007 History of Changes

Sponsored by:	University of Colorado at Denver and Health Sciences Center
Information provided by:	University of Colorado at Denver and Health Sciences Center
ClinicalTrials.gov Identifier:	NCT00453258

Purpose

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film from diseased and non-diseased patients. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Condition
Eye Disease

Study Type:	Observational
Study Design:	Natural History, Cross-Sectional, Defined Population, Prospective Study
Official Title:	Analysis of Human Tear Proteins: A Pilot Study to Describe the Tear Film Proteome of Patients Undergoing Ophthalmic Examination.

Resource links provided by NLM:

MedlinePlus related topics: Eye Diseases

U.S. FDA Resources

Further study details as provided by University of Colorado at Denver and Health Sciences Center:

Estimated Enrollment:	100
Study Start Date:	February 2007

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

18 years of age and older
able to cooperate with tear sample collection
provide written informed consent

Exclusion Criteria:

special populations (chidren, pregnant or lactating females, prisoners, etc)
refusal to sign sudy consent

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00453258

Contacts

Contact: Tim Byrne	720-848-5051	tim.byrne@uchsc.edu
Contact: Malik Y. Kahook, MD	720-848-5029	malik.kahook@uchsc.edu

Locations

United States, Colorado
Rocky Mountain Lions Eye Institute	Recruiting
Aurora, Colorado, United States, 80045
Contact: Tim Byrne 720-848-5051 tim.byrne@uchsc.edu
Contact: Malik Y. Kahook, MD 720-848-5029 malik.kahook@uchsc.edu
Principal Investigator: Malik Y. Kahook, MD
Sub-Investigator: Naresh Mandava, MD
Sub-Investigator: Mark Duncan, MD
Sub-Investigator: Vikram Durairaj, MD

Sponsors and Collaborators

University of Colorado at Denver and Health Sciences Center

Investigators

Principal Investigator:

Malik Y. Kahook, MD

Rocky Mountain Lions Eye Institute

More Information

No publications provided

Study ID Numbers:	myk06-0862
Study First Received:	March 26, 2007
Last Updated:	March 27, 2007
ClinicalTrials.gov Identifier:	NCT00453258 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Colorado at Denver and Health Sciences Center:

ocular proteomics
eye disease
proteomics

Study placed in the following topic categories:

Lacerations
Eye Diseases

Additional relevant MeSH terms:

Eye Diseases

ClinicalTrials.gov processed this record on September 10, 2009