Coronary Artery Disease and Sleep Apnea

This study has been completed.

First Received: November 21, 2007 Last Updated: July 1, 2008 History of Changes

Sponsors and Collaborators:	Umeå University Swedish Heart Lung Foundation Swedish Heart- and Lung Association Norrländska Hjärtfonden Jämtland County Council
Information provided by:	Umeå University
ClinicalTrials.gov Identifier:	NCT00562679

Purpose

The purpose of this study is to determine the effect of sleep apnea on mortality, stroke and myocardial infarction among 408 patients with coronary artery disease referred for evaluation of coronary intervention who were examined with overnight cardio respiratory monitoring between March 1992 and June 1995.

Condition	Intervention
Coronary Artery Disease	Other: There is no intervention

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Long Term Effects of Sleep Apnea in Patients With Coronary Artery Disease

Resource links provided by NLM:

MedlinePlus related topics: Coronary Artery Disease Heart Attack Sleep Apnea

U.S. FDA Resources

Further study details as provided by Umeå University:

Primary Outcome Measures:

Stroke, death, acute myocardial infarction [ Time Frame: 10 years from date of inclusion ]

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	408
Study Start Date:	March 1992
Study Completion Date:	October 2007

Groups/Cohorts	Assigned Interventions
2 groups The cohort is grouped according to one group with sleep apnea and one group without sleep apnea	Other: There is no intervention not applicable

Eligibility

Ages Eligible for Study:	up to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Patiens with coronary artery disease beeing referred for evaluation of coronary intervention

Criteria

Inclusion Criteria:

Men and women younger than 70 with disabling angina pectoris and coronary disease according to coronary angiography.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00562679

Locations

Sweden
Dept of Cardiology
Umeå, Sweden, SE 901 85

Sponsors and Collaborators

Umeå University

Swedish Heart Lung Foundation

Swedish Heart- and Lung Association

Norrländska Hjärtfonden

Jämtland County Council

Investigators

Principal Investigator:

Thomas Mooe, MD, PhD

Dept Medicine, Östersund Hospital, Östersund

More Information

No publications provided by Umeå University

Additional publications automatically indexed to this study by National Clinical Trials Identifier (NCT ID):

Valham F, Mooe T, Rabben T, Stenlund H, Wiklund U, Franklin KA. Increased risk of stroke in patients with coronary artery disease and sleep apnea: a 10-year follow-up. Circulation. 2008 Aug 26;118(9):955-60. Epub 2008 Aug 12.

Study ID Numbers:	93-032
Study First Received:	November 21, 2007
Last Updated:	July 1, 2008
ClinicalTrials.gov Identifier:	NCT00562679 History of Changes
Health Authority:	Sweden: The National Board of Health and Welfare

Keywords provided by Umeå University:

Patients with coronary artery disease

Study placed in the following topic categories:

Arterial Occlusive Diseases
Sleep Apnea Syndromes
Heart Diseases
Apnea
Myocardial Ischemia
Respiration Disorders
Vascular Diseases
Dyssomnias

Sleep Disorders
Ischemia
Arteriosclerosis
Sleep Disorders, Intrinsic
Coronary Disease
Respiratory Tract Diseases
Coronary Artery Disease

Additional relevant MeSH terms:

Arterial Occlusive Diseases
Sleep Apnea Syndromes
Heart Diseases
Apnea
Myocardial Ischemia
Nervous System Diseases
Respiration Disorders
Vascular Diseases

Sleep Disorders
Dyssomnias
Arteriosclerosis
Sleep Disorders, Intrinsic
Coronary Disease
Respiratory Tract Diseases
Cardiovascular Diseases
Coronary Artery Disease

ClinicalTrials.gov processed this record on September 10, 2009