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Sponsored by: |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
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Information provided by: | Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
ClinicalTrials.gov Identifier: | NCT00716222 |
There is a well-documented relationship between short sleep duration and high body mass index (BMI). The mechanism linking short sleep duration and weight gain is unknown. Current studies in healthy young volunteers have shown that experimental sleep restriction is associated with dysregulation of the neuroendocrine control of appetite and with alterations in glucose metabolism. The goal of our study is to determine the metabolic and hormonal modifications induced by chronic sleep curtailment in obese adolescents and young adults and to observe if short sleep is a negative prognostic factor in their weight evolution.
Condition |
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Obesity Sleep Disorders |
Study Type: | Observational |
Study Design: | Cohort, Cross-Sectional |
Official Title: | Hormonal and Metabolic Consequences of Sleep Disorders in Young Obese Patients |
Estimated Enrollment: | 70 |
Study Start Date: | May 2008 |
Estimated Study Completion Date: | May 2009 |
Groups/Cohorts |
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1
Obese adolescent and young adult with sleep disorder
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2
Obese adolescent and young adult without sleep disorder
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3
Lean adolescent and young adult with sleep disorder
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The main purpose of the study is investigate whether the concentrations of 2 hormones that regulate appetite (leptin, ghrelin), cytokines (TNF-a, IL-6) and CRP are modified in obese adolescents and young adults who had sleep disorders in comparison to obese adolescents and young adults who sleep longer.
Ages Eligible for Study: | 13 Years to 25 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patients of the output clinics in the endocrinology and pediatric endocrinology departments at the university hospital.
Inclusion Criteria:
Exclusion Criteria:
Contact: Veronique VB Beauloye, PhD | +3227641370 | Veronique.Beauloye@uclouvain.be |
Belgium | |
Cliniques Universitaires Saint Luc | Recruiting |
Brussels, Belgium, 1200 | |
Contact: Veronique VB Beauloye, PhD +3227641370 Veronique.Beauloye@uclouvain.be |
Principal Investigator: | Veronique Beauloye, PhD | Cliniques Universitaires Saint Luc |
Responsible Party: | Cliniques universitaires Saint-Luc ( M.D. PhD V Beauloye ) |
Study ID Numbers: | B40320084032 |
Study First Received: | July 15, 2008 |
Last Updated: | January 20, 2009 |
ClinicalTrials.gov Identifier: | NCT00716222 History of Changes |
Health Authority: | Belgium: Institutional Review Board |
Body Weight Signs and Symptoms Obesity Mental Disorders Neurologic Manifestations |
Nutrition Disorders Sleep Disorders Overweight Overnutrition |
Body Weight Signs and Symptoms Obesity Pathologic Processes Disease Mental Disorders |
Nervous System Diseases Neurologic Manifestations Nutrition Disorders Sleep Disorders Overweight Overnutrition |