Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
AstraZeneca |
---|---|
Information provided by: | AstraZeneca |
ClinicalTrials.gov Identifier: | NCT00251979 |
This study is being carried out to see if constant 3 days infusion of Nexium is effective in preventing rebleeding after an endoscopic treatment.
Condition | Intervention | Phase |
---|---|---|
Gastrointestinal Hemorrhage |
Drug: Esomeprazole |
Phase III |
Study Type: | Interventional |
Study Design: | Prevention, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | A Randomised, Double-Blind, Parallel-Group, Placebo Controlled Study of Esomeprazole i.v. (Bolus Infusion of 80 mg Followed by a Continuous Infusion of 8 mg Per Hour) Administered for 72 Hours to Assess Prevention of Rebleeding in Subjects That Have Undergone Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer - the PUB Study. |
Estimated Enrollment: | 760 |
Study Start Date: | October 2005 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Study Director: | AstraZeneca Nexium Medical Sciences Director | AstraZeneca |
Principal Investigator: | Joseph Sung, MD | Chinese University of Hong Kong |
Study ID Numbers: | D961DC00001 |
Study First Received: | November 9, 2005 |
Last Updated: | January 10, 2008 |
ClinicalTrials.gov Identifier: | NCT00251979 History of Changes |
Health Authority: | Sweden: Medical Products Agency |
Stomach Diseases Digestive System Diseases Gastrointestinal Diseases Ulcer Peptic Ulcer Hemorrhage Gastrointestinal Hemorrhage |
Omeprazole Intestinal Diseases Hemorrhage Hemostatics Duodenal Diseases Peptic Ulcer |
Molecular Mechanisms of Pharmacological Action Gastrointestinal Diseases Gastrointestinal Hemorrhage Gastrointestinal Agents Omeprazole Enzyme Inhibitors Hemorrhage Intestinal Diseases Pharmacologic Actions |
Digestive System Diseases Pathologic Processes Stomach Diseases Therapeutic Uses Peptic Ulcer Hemorrhage Anti-Ulcer Agents Peptic Ulcer Duodenal Diseases |