Monitoring of Intubation and Ventilation During Resuscitation

This study has been completed.

First Received: September 12, 2005 Last Updated: August 24, 2007 History of Changes

Sponsors and Collaborators:	University of Oslo Laerdal Medical Ullevaal University Hospital Health Region East, Norway Norwegian Air Ambulance Foundation Stavanger University Hospital
Information provided by:	University of Oslo
ClinicalTrials.gov Identifier:	NCT00204217

Purpose

Airway control and ventilation is vital during cardiopulmonary resuscitation (CPR) in cardiac arrest.

Endotracheal intubation is the gold standard for airway control, but several studies have shown high rates of unrecognized placements of the tube in the esophagus instead of in the airway out-of-hospital. This is lethal.

There are no failproof technique for recognising such mistakes clinically in the cardiac arrest situation.

Changes on the air volume in the lungs with ventilation changes the impedance (resistance to alternating current) through the thorax. This impedance is already measured routinely by the defibrillators used during CPR. We propose that we can measure ventilation volumes and also discover failed intubations by monitoring this impedance during CPR with the possibility of giving feedback on both to the rescuers.

Condition	Intervention	Phase
Cardiac Arrest	Device: endotracheal intubation	Phase II

Study Type:	Interventional
Study Design:	Diagnostic, Non-Randomized, Open Label, Uncontrolled, Crossover Assignment, Efficacy Study
Official Title:	Monitoring of Intubation and Ventilation During Resuscitation

Further study details as provided by University of Oslo:

Primary Outcome Measures:

sensitivity/specificity for lung ventilation detection
correlation ventilation volume - impedance change

Estimated Enrollment:	15
Study Start Date:	September 2004
Study Completion Date:	April 2007

Detailed Description:

On the anesthesiologist manned ambulance in Oslo ventilation volumes during CPR will be controlled with a ventilator, the tidal volume varied in random order between 500, 700 and 100 ml, and the volumes be measured continuously as will the impedance between the defibrillator electrodes. In case of failed CPR, the patient will be declared dead. Thereafter the lungs will be ventilated with 700 ml followed by removal of the endotracheal tube, placement of an endotracheal tube in the esophagus and ventilation of this tube, again with monitoring of the impedance.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Cardiac arrest

Exclusion Criteria:

<18 years old trauma pregnancy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00204217

Locations

Norway
Ulleval University Hospital
Oslo, Norway, N-0407

Sponsors and Collaborators

University of Oslo

Laerdal Medical

Ullevaal University Hospital

Health Region East, Norway

Norwegian Air Ambulance Foundation

Stavanger University Hospital

Investigators

Principal Investigator:

Elizabeth Dorph

Ulleval University Hospital, University of Oslo

More Information

No publications provided

Study ID Numbers:	313-04124
Study First Received:	September 12, 2005
Last Updated:	August 24, 2007
ClinicalTrials.gov Identifier:	NCT00204217 History of Changes
Health Authority:	Norway: The National Committees for Research Ethics in Norway

Keywords provided by University of Oslo:

cardiac arrest
resuscitation
ventilation
impedance

Study placed in the following topic categories:

Heart Diseases
Heart Arrest

Additional relevant MeSH terms:

Heart Diseases
Cardiovascular Diseases
Heart Arrest

ClinicalTrials.gov processed this record on September 10, 2009