NIDA - Research Monographs - Monograph 121: Buprenorphine: An Alternative Treatment for Opioid Dependence

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	Buprenorphine: An Alternative Treatment for Opioid Dependence

NIDA Research Monograph, Number 121 [Printed in 1992]

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Introduction-----1
Jack O. Blaine

Buprenorphine-Background to Its Development as a Treatment for Opiate Dependence-----5
John W. Lewis and Donald Walter

Behavioral Pharmacology of Buprenorphine: Issues Relevant to Its Potential in Treating Drug Abuse-----12
James H. Woods, Charles P. France, and Gail D. Winger

Assessment of Buprenorphine in a Drug Discrimination Procedure in Humans-----28
George E. Bigelow and Kenzie L. Preston

Human Laboratory Studies of Buprenorphine-----38
Jack H. Menedelson and Nancy K. Mello

Primate Studies of the Behavioral Pharmacology of Buprenorphine-----61
Nancy K. Mello and Jack H. Mendelson

Phase II Clinical Trials of Buprenorphine: Detoxification and Induction Onto Naltrexone-----101
Thomas R. Kosten, Charles Morgan, and Herbert D. Kleber

Development of Buprenophine for the Treatment of Opioid Dependence-----120
Rolley E. Johnson and Paul J. Fudala

List of NIDA Research Monographs-----142

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