Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
Sun Yat-sen University |
---|---|
Information provided by: | Sun Yat-sen University |
ClinicalTrials.gov Identifier: | NCT00720668 |
This study aim to find out the risk of exacerbation of chronic hepatitis B after percutaneous radiofrequency ablation (RFA) or hepatectomy for HCC, and it's effect to treatment outcome.
Condition | Intervention |
---|---|
Hepatitis B Hepatocellular Carcinoma |
Procedure: radiofrequency ablation |
Study Type: | Observational |
Study Design: | Case-Only, Prospective |
Official Title: | The Risk of Exacerbation of Chronic Hepatitis B After Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma |
Estimated Enrollment: | 200 |
Study Start Date: | June 2006 |
Estimated Study Completion Date: | May 2010 |
Estimated Primary Completion Date: | March 2009 (Final data collection date for primary outcome measure) |
Groups/Cohorts | Assigned Interventions |
---|---|
1
patient with hepatocellular carcinoma after radiofrequency ablation
|
Procedure: radiofrequency ablation
radiofrequency ablation for HCC
|
It has been reported that HBV replication can be reacted after chemotherapy or immunotherapy, which will lead to exacerbation of chronic hepatitis B (ECHB). It is still unknown that if percutaneous radiofrequency ablation or liver resection for hepatocellular carcinoma (HCC) will react the replication of HBV or not. This study aim to find out the risk of exacerbation of chronic hepatitis B after percutaneous radiofrequency ablation (RFA) or hepatectomy for HCC, and it's effect to treatment outcome.
Ages Eligible for Study: | 18 Years to 75 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
patients with hepatocellular carcinoma (HCC) after percutaneous radiofrequency ablation.
Inclusion Criteria:
Exclusion Criteria:
Contact: min-shan chen, MD | 86-20-87343117 ext 86-20-87343117 | Chminsh@mail.sysu.edu.cn |
China, Guangdong | |
Cancer Center, Sun Yat-sen University | Recruiting |
Guangzhou, Guangdong, China, 510060 | |
Contact: Min-Shan Chen, MD 86-20-87343117 ext 86-20-87343117 Chminsh@mail.sysu.edu.cn | |
Contact: Min-Shan Chen, MD 86-20-87343117 ext 86-20-87343117 Chminsh@mail.sysu.edu.cn | |
Principal Investigator: Min-Shan Chen, MD | |
Sub-Investigator: Yao-Jun Zhang, Doctor |
Principal Investigator: | min-shan chen, MD | Department of Hepatobilliary Surgery, Cancer Center, Sun Yat-sen University |
Responsible Party: | cancer canter, Sun Yat-sen University ( minshan chen ) |
Study ID Numbers: | RFA006 |
Study First Received: | July 21, 2008 |
Last Updated: | February 6, 2009 |
ClinicalTrials.gov Identifier: | NCT00720668 History of Changes |
Health Authority: | China: Ministry of Health |
hepatitis B hepatocellular carcinoma radiofrequency ablation reactivation |
Liver Diseases Digestive System Neoplasms Hepatitis, Chronic Carcinoma, Hepatocellular Hepatitis, Viral, Human Carcinoma Liver Neoplasms Hepatitis Virus Diseases |
Digestive System Diseases Hepatitis B, Chronic Hepatitis B Gastrointestinal Neoplasms DNA Virus Infections Hepatocellular Carcinoma Adenocarcinoma Neoplasms, Glandular and Epithelial |
Liver Diseases Digestive System Neoplasms Neoplasms by Histologic Type Hepatitis, Chronic Carcinoma, Hepatocellular Hepatitis, Viral, Human Hepadnaviridae Infections Carcinoma Liver Neoplasms Virus Diseases |
Hepatitis Neoplasms Neoplasms by Site Digestive System Diseases Hepatitis B, Chronic Hepatitis B DNA Virus Infections Adenocarcinoma Neoplasms, Glandular and Epithelial |