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Sponsored by: |
Children's Healthcare of Atlanta |
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Information provided by: | Children's Healthcare of Atlanta |
ClinicalTrials.gov Identifier: | NCT00229827 |
The purpose of this study is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.
Condition |
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Ventricular Septal Defects Persistent Common Atrioventricular Canal |
Study Type: | Observational |
Study Design: | Natural History, Longitudinal, Defined Population, Retrospective Study |
Official Title: | Optimal Timing for Repair of Left-to-Right Shunt Lesions |
Estimated Enrollment: | 200 |
Study Start Date: | May 2005 |
In the past, children with left-to-right shunt lesions such as ventricular septal defects and atrioventricular canal defects were palliated with a pulmonary artery band. This prevented injury to the pulmonary vasculature while the child grew to a size where complete repair could be undertaken. With the improvements in surgical technique and critical care, there is a push to do a primary complete repair for these defects at younger and younger ages. These operations should be delayed as long as possible to allow for growth but not so long that there is unnecessary heart failure and medication requirements. The primary aim is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.
The secondary aim is to define the criteria for failing medical anti-congestive heart failure therapy. This study will be conducted through a retrospective chart review.
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
United States, Georgia | |
Children's Healthcare of Atlanta at Egleston | |
Atlanta, Georgia, United States, 30322 |
Principal Investigator: | Brian Kogon, MD | Emory University |
Study ID Numbers: | 05-092 |
Study First Received: | September 13, 2005 |
Last Updated: | May 22, 2007 |
ClinicalTrials.gov Identifier: | NCT00229827 History of Changes |
Health Authority: | United States: Institutional Review Board |
pediatric health cardiac pediatric population congenital heart surgery |
left to right shunt lesions heart surgery Atrioventricular canal defects |
Heart Septal Defects Complete Atrioventricular Canal Heart Diseases Cardiovascular Abnormalities Heart Septal Defects, Ventricular |
Ventricular Septal Defects Congenital Heart Septum Defect Endocardial Cushion Defects Congenital Abnormalities Heart Defects, Congenital |
Heart Septal Defects Heart Diseases Cardiovascular Abnormalities Heart Septal Defects, Ventricular |
Cardiovascular Diseases Endocardial Cushion Defects Congenital Abnormalities Heart Defects, Congenital |