High-Resolution Optical Coherence Tomography for Detection of Retinal Nerve Fiber Layer Loss in Band Atrophy of the Optic Nerve

This study is ongoing, but not recruiting participants.

First Received: February 4, 2008 Last Updated: November 11, 2008 History of Changes

Sponsored by:	University of Sao Paulo
Information provided by:	University of Sao Paulo
ClinicalTrials.gov Identifier:	NCT00607100

Purpose

The purpose of this study is to compare the abilities of high-speed,high-resolution (HR) optical coherence tomography (OCT) and Stratus OCT for detection of retinal nerve fiber layer (RNFL) loss in eyes with band atrophy (BA) of the optic nerve.

Condition
Band Atrophy Chiasmal Compression Neural Loss

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	High-Resolution Optical Coherence Tomography for Detection of Retinal Nerve Fiber Layer Loss in Band Atrophy of the Optic Nerve

Further study details as provided by University of Sao Paulo:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	30
Study Start Date:	December 2007
Estimated Study Completion Date:	December 2008
Estimated Primary Completion Date:	March 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Patients with Band atrophy of the optic nerve
2 Normal Controls

Eligibility

Ages Eligible for Study:	18 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Patients with band atrophy from chismal compression and controls

Criteria

Inclusion Criteria:

Visual acuity better than 20/30
Refractive error less 5 spherical diopter and 3 cylinder diopter
Temporal field defect

Exclusion Criteria:

Presence of glaucoma and optic nerve anomalies
A normal nasal field

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00607100

Locations

Brazil
University of São Paulo - Ophthalmology Department
São Paulo, Brazil, 05403-000

Sponsors and Collaborators

University of Sao Paulo

Investigators

Principal Investigator:

Luciana Costa Cunha, MD

University of São Paulo

More Information

No publications provided by University of Sao Paulo

Additional publications automatically indexed to this study by National Clinical Trials Identifier (NCT ID):

Costa-Cunha LV, Cunha LP, Malta RF, Monteiro ML. Comparison of Fourier-domain and time-domain optical coherence tomography in the detection of band atrophy of the optic nerve. Am J Ophthalmol. 2009 Jan;147(1):56-63.e2. Epub 2008 Sep 6.

Responsible Party:	University of São Paulo ( Mario Luiz Ribeiro Monteiro, Phd )
Study ID Numbers:	CAPPESQ N. 1056/07
Study First Received:	February 4, 2008
Last Updated:	November 11, 2008
ClinicalTrials.gov Identifier:	NCT00607100 History of Changes
Health Authority:	Brazil: National Committee of Ethics in Research

Keywords provided by University of Sao Paulo:

High-Resolution Optical Coherence Tomography
Retinal Nerve Fiber Layer
Band Atrophy

Study placed in the following topic categories:

Pathological Conditions, Anatomical
Atrophy

Additional relevant MeSH terms:

Pathological Conditions, Anatomical
Atrophy

ClinicalTrials.gov processed this record on September 03, 2009