A Study to Investigate a Research Drug as an Aid for Smoking Cessation in Chronic Cigarette Smokers

This study has been completed.

First Received: April 22, 2005 Last Updated: May 13, 2008 History of Changes

Sponsored by:	Merck
Information provided by:	Merck
ClinicalTrials.gov Identifier:	NCT00109135

Purpose

The purpose of this study is to evaluate the safety and tolerability of an investigational drug that may help individuals to stop smoking.

Condition	Intervention	Phase
Smoking	Drug: taranabant	Phase II

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double Blind (Subject, Investigator), Placebo Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	A Double-Blind, Multicenter, Randomized, Titrated-Dose, Placebo-Controlled, Study of MK0364 (4 mg to 8 mg) in Chronic Cigarette Smokers as an Aid for Smoking Cessation

Resource links provided by NLM:

MedlinePlus related topics: Quitting Smoking Smoking

Further study details as provided by Merck:

Primary Outcome Measures:

Quitting smoking after 8 weeks of treatment by measuring lab values and expired breath CO levels [ Time Frame: after 8 weeks of treatment ] [ Designated as safety issue: No ]

Enrollment:	300
Study Start Date:	April 2004
Primary Completion Date:	June 2005 (Final data collection date for primary outcome measure)

Eligibility

Criteria

Inclusion Criteria:

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00109135

Sponsors and Collaborators

Merck

Investigators

Study Director:

Medical Monitor

Unaffiliated

More Information

No publications provided

Responsible Party:	Merck & Co., Inc. ( Executive Vice President, Clinical and Quantitative Sciences )
Study ID Numbers:	2005_012, MK0364-007
Study First Received:	April 22, 2005
Last Updated:	May 13, 2008
ClinicalTrials.gov Identifier:	NCT00109135 History of Changes
Health Authority:	United States: Food and Drug Administration

Study placed in the following topic categories:

Smoking

Additional relevant MeSH terms:

Habits
Smoking

ClinicalTrials.gov processed this record on September 03, 2009