Chemotherapy, Hormone Therapy, and Surgery to Remove the Prostate Gland in Patients With High Risk Prostate Cancer

This study has been completed.

First Received: April 14, 2005 Last Updated: April 2, 2008 History of Changes

Sponsored by:	Department of Veterans Affairs
Information provided by:	Department of Veterans Affairs
ClinicalTrials.gov Identifier:	NCT00108290

Purpose

In men with prostate cancer who do not have evidence of spread to bone or other sites on computed axial tomography (CAT) scan/bone scan but are still at significant risk of failing treatment with surgery or radiation alone, a combination of chemotherapy and hormone therapy is being given for 6 months followed by surgery to remove the prostate.

Condition	Intervention	Phase
Prostate Cancer	Drug: Chemotherapy	Phase II

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Official Title:	Chemohormone Therapy Prior to Prostatectomy in High Risk Prostate Cancer

Resource links provided by NLM:

MedlinePlus related topics: Cancer Prostate Cancer Surgery

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Study Start Date:	April 2004
Estimated Study Completion Date:	March 2007

Eligibility

Ages Eligible for Study:	18 Years to 80 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

High risk prostate cancer without evidence of bone metastasis.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00108290

Locations

United States, Maryland
VA Maryland Health Care System
Baltimore, Maryland, United States, 21201

Sponsors and Collaborators

Department of Veterans Affairs

More Information

No publications provided

Study ID Numbers:	CLIN-003-02F
Study First Received:	April 14, 2005
Last Updated:	April 2, 2008
ClinicalTrials.gov Identifier:	NCT00108290 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by Department of Veterans Affairs:

Prostate cancer
chemotherapy
hormone therapy

surgery
PSA
Gleason score

Study placed in the following topic categories:

Prostatic Diseases
Genital Neoplasms, Male
Urogenital Neoplasms

Genital Diseases, Male
Hormones
Prostatic Neoplasms

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site
Prostatic Diseases
Genital Neoplasms, Male

Urogenital Neoplasms
Genital Diseases, Male
Prostatic Neoplasms

ClinicalTrials.gov processed this record on September 03, 2009