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National Institutes of Health

NIMH Pages about Depression

Learn more about Depression…

Clinical Trials Page

Find current studies on Depression…

Publications

Looking at My Genes: What Can They Tell Me?
A fact sheet containing frequently asked questions about genome scans and genetic testing.
Date: 2008
Women and Depression: Discovering Hope
A booklet that describes the symptoms, treatment and factors contributing to depression that are unique to women.
Date: 2008
También disponible en Español
Depression (Easy to Read)
An easy-to-read booklet on Depression that explains what it is, when it starts, how long it lasts, and how to get help.
Date: 2007
También disponible en Español
Depression
A detailed booklet that describes Depression symptoms, causes, and treatments, with information on getting help and coping.
Date: 2007
También disponible en Español
Men and Depression
A detailed booklet that describes what you need to know about depression in men: how it looks, how it feels, getting help, and getting better.
Date: 2005
También disponible en Español

More Publications…

Science News

Combination Treatment for Psychotic Depression Holds Promise
August 07, 2009 • Science Update
A combination of an atypical antipsychotic medication and an antidepressant known as a selective serotonin reuptake inhibitor (SSRI) may be more effective in treating psychotic depression than an atypical antipsychotic alone, according to results from an NIMH-funded clinical study.
Brain Emotion Circuit Sparks as Teen Girls Size Up Peers
July 15, 2009 • Press Release
What is going on in teenagers’ brains as their drive for peer approval begins to eclipse their family affiliations? Brain scans of teens sizing each other up reveal an emotion circuit activating more in girls as they grow older, but not in boys. The study by Daniel Pine, M.D., of the National Institute of Mental Health (NIMH), part of National Institutes of Health, and colleagues, shows how emotion circuitry diverges in the male and female brain during a developmental stage in which girls are at increased risk for developing mood and anxiety disorders.
Much Touted “Depression Risk Gene” May Not Add to Risk After All
June 16, 2009 • Press Release
Stressful life events are strongly associated with a person’s risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect, according to researchers funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health. The study, published in the June 17, 2009, issue of the Journal of the American Medical Association, challenges a widely accepted approach to studying risk factors for depression.
Re-shaping Negative Thoughts Shields At-Risk Teens from Depression
June 09, 2009 • Science Update
At-risk teens exposed to a program that teaches them to counteract their unrealistic and overly negative thoughts experienced significantly less depression than their peers who received usual care, NIMH-funded researchers have found. However, the cognitive behavioral prevention program failed to similarly help adolescents prone to the mood disorder if their parents were currently depressed.
New NIMH Video Describes Depression, Importance of Treatment
June 02, 2009 • Science Update
A new 4-minute video from the National Institute of Mental Health provides an overview for the general public on the symptoms, impact, and treatment of depression. The video is available for viewing by individuals or can be used by community groups or in health care offices to inform viewers about depression and its consequences, and the critical importance of seeking treatment.

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Meeting Summaries

Perinatal Mood Disorders: Components of Care
May 07, 2009 – May 08, 2009
Bethesda, Maryland
A two-day meeting convened in May 2009 educated participants on essential components of care for women with perinatal mood disorders
Research Roundtable: Heterogeneity in Child and Adolescent Depression
February 18, 2008 – February 19, 2008
Washington, DC
The purpose of this workshop was to discuss empirical evidence for sources of heterogeneity in child and adolescent depression, evaluate the significance of known heterogeneity, and identify promising research directions in this area.
Benefits, Limitations, and Emerging Research Needs in Treating Youth with Depression
February 06, 2006 – February 07, 2006
Washington, DC
On February 6 and 7, 2006, experts in child and adolescent depression met in Washington, DC to review the state of the science of the treatment of youth depression and discuss approaches to further research.
Treating Children and Adolescents with Depression: Future Research Questions
February 01, 2006
Washington, DC
In February 2006, NIMH hosted this two-day workshop with the purpose of reviewing the evidence for benefits and risks of existing treatment interventions for youths suffering from depression, identifying knowledge gaps in need of further research, and discussing approaches to future research with respect to design, methods, and implementation.

More Meeting Summaries…