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| Sponsors and Collaborators: |
University of Konstanz vivo |
|---|---|
| Information provided by: | University of Konstanz |
| ClinicalTrials.gov Identifier: | NCT00623298 |
Purpose
The present study is a pragmatic trial that investigates the efficacy and usefulness of two treatment modules in a sample of Rwandan genocide orphans: Narrative Exposure Therapy (NET) versus group-Interpersonal Psychotherapy (IPT). We used a half year baseline to measure the treatment-induced changes. We hypothesized that there would be a greater reduction in posttraumatic stress symptoms in the NET- than in the IPT-group and that IPT would be superior to NET in the reduction of depression symptoms.
| Condition | Intervention | Phase |
|---|---|---|
|
Posttraumatic Stress Disorder Depression Narrative Exposure Therapy Interpersonal Psychotherapy |
Behavioral: Narrative Exposure Therapy Behavioral: group IPT Other: 6 months-baseline |
Phase II |
| Study Type: | Interventional |
| Study Design: | Treatment, Non-Randomized, Single Blind (Outcomes Assessor), Active Control |
| Official Title: | Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy -A Controlled Clinical Trial With Orphaned Survivors of the Rwandan Genocide |
| Enrollment: | 26 |
| Study Start Date: | January 2005 |
| Study Completion Date: | March 2006 |
| Arms | Assigned Interventions |
|---|---|
|
1: Experimental
NET
|
Behavioral: Narrative Exposure Therapy |
|
3: No Intervention
6-months baseline
|
Other: 6 months-baseline |
|
2: Experimental
group IPT
|
Behavioral: group IPT |
The 1994 genocide of Rwanda has left countless children orphaned. 26 Rwandan orphans who fulfilled DSM-IV diagnosis of PTSD were offered participation in a controlled treatment trial. A group adaptation of Interpersonal Psychotherapy (IPT, n = 14) was compared to Narrative Exposure Therapy (NET, n = 12). Main outcome measures were symptoms of PTSD and depression assessed pre-treatment, 3 months after therapy (post-test) and 6 months after therapy (follow-up) using the CAPS, MINI and Hamilton Rating Scale. At post-test, participants in both treatment conditions showed reductions in posttraumatic stress symptoms and depression symptoms. At 6-month follow-up, NET proved to be more effective in the treatment of PTSD. Only 25% (n = 3) of NET-participants but 71% (n = 10) of the IPT-participants still fulfilled PTSD criteria at follow-up. Although there was a significant reduction in depression symptoms in both treatment groups from pre-test to follow-up, NET again proved to be more effective.
This treatment-trial demonstrates that NET and group-IPT are suitable treatment modules even when most severe traumatic stress and difficult living conditions have led to chronic mental suffering.
Eligibility| Ages Eligible for Study: | 13 Years to 29 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations More Information
| Responsible Party: | University of Konstanz, vivo ( Dr. Susanne Schaal ) |
| Study ID Numbers: | Fogr SOSS |
| Study First Received: | February 14, 2008 |
| Last Updated: | February 25, 2008 |
| ClinicalTrials.gov Identifier: | NCT00623298 History of Changes |
| Health Authority: | University of Konstanz: Germany |
|
Posttraumatic stress disorder depression Narrative Exposure Therapy Interpersonal Psychotherapy |
|
Depression Anxiety Disorders Mental Disorders Mood Disorders Stress Disorders, Post-Traumatic |
Stress Depressive Disorder Stress Disorders, Traumatic Behavioral Symptoms |
|
Depression Anxiety Disorders Mental Disorders Mood Disorders |
Stress Disorders, Post-Traumatic Depressive Disorder Stress Disorders, Traumatic Behavioral Symptoms |
