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NHGRI Affiliated CentersNHGRI, in collaboration with other components of the National Institutes of Health, is closely associated with several major centers involved in genome research. These affiliated centers are: Center for Inherited Disease Research [cidr.jhmi.edu] The Center for Inherited Disease Research (CIDR) is a centralized facility established to provide genotyping and statistical genetics services for investigators seeking to identify genes that contribute to human disease. CIDR concentrates primarily on multifactorial hereditary disease although linkage analysis of single gene disorders can also be accommodated. CIDR was established in 1996 as a joint effort by eight institutes at the National Institutes of Health (NIH). Three additional institutes joined the effort in 1999, and another in 2000. Mouse genotyping services were added in 2000. An application for CIDR Services is welcome from any investigator, world-wide. Access to CIDR is through a peer-review process. Center for Research on Genomics and Global Health [crggh.nih.gov]The Center for Research on Genomics and Global Health (CRGGH) aims to facilitate a global understanding of the relationship between human genetic variation and population differences in disease distribution, with the ultimate goal of informing health disparities. Investigators in the CRGGH will develop genetic epidemiology models that will explore the patterns and determinants of common complex diseases in populations in the United States and other human populations around the world. The establishment of the CRGGH, a trans-National Institutes of Health (NIH) effort, brings about an opportunity for it to be a leader in public awareness regarding how genomics is informing health and human history. National Institutes of Health (NIH) Chemical Genomics Center [ncgc.nih.gov] Established in 2004, the NIH Chemical Genomics Center (NCGC) will apply the tools of small molecule screening and discovery to the development of chemical probe research tools, for use in the study of protein and cell functions, and biological processes relevant to physiology and disease. NCGC will optimize biochemical, cellular and model organism-based assays submitted by the biomedical research community; perform automated high-throughput screening (HTS); and perform chemistry optimization on confirmed hits to produce chemical probes for dissemination to the research community. National Institutes of Health (NIH) Intramural Sequencing Center [nisc.nih.gov] The NIH Intramural Sequencing Center (NISC), established in 1997, is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing investigators at the NIH access to large-scale DNA sequencing, NISC plays a major role in several efforts related to the Human Genome Project. These include a Comparative Vertebrate Sequencing Initiative, the ENCODE Project, and the Mammalian Gene Collection Program.
Last Updated: April 14, 2009 |