![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
![]() |
Sponsors and Collaborators: |
National Institute on Aging (NIA) Ohio State University |
---|---|
Information provided by: | National Institute on Aging (NIA) |
ClinicalTrials.gov Identifier: | NCT00385723 |
This study is designed to examine the effects of fish oil on immune function and mood.
Condition | Intervention | Phase |
---|---|---|
Inflammation |
Dietary Supplement: Omega 3 (Fish Oil) Supplementation Dietary Supplement: Placebo |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double Blind (Subject, Investigator, Outcomes Assessor), Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | Omega-3 Dietary Supplementation, Immune Function, and Mood |
Estimated Enrollment: | 138 |
Study Start Date: | September 2006 |
Estimated Study Completion Date: | December 2010 |
Estimated Primary Completion Date: | December 2010 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
1: Experimental
1.25 g/d
|
Dietary Supplement: Omega 3 (Fish Oil) Supplementation
1.25 g or 2.496 g daily for 4 months
|
2: Experimental
2.496 g/d
|
Dietary Supplement: Omega 3 (Fish Oil) Supplementation
1.25 g or 2.496 g daily for 4 months
|
3: Placebo Comparator |
Dietary Supplement: Placebo
matching placebo capsule daily for 4 months
|
The beneficial effects of fish oil (or eating fish more frequently) include reductions in triglycerides, blood pressure, and heart rate, as well as increases in HDL cholesterol, the "good" type of cholesterol. In addition, certain aspects of immune function also appear to show favorable responses to fish oil supplementation, and some studies suggest that fish oil helps to improve mood and decrease depression.
This study is designed to examine how supplementation with omega-3 polyunsaturated fatty acids (key fish oil components) affects aspects of your immune response, and your mood; because some research suggests that people who eat more fish may do better during stressful times, the study will also examine how fish oil affects your immune response to stress, certain stress hormone responses, and your psychological response to stress.
For detailed information about the study, please visit our website at http://www.stressandhealth.org
Ages Eligible for Study: | 40 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Recruiting men and women ages 50-80 from the Greater Columbus Ohio area. Participation involves taking capsules for 4 months and completing 7 appointments (for a total of 17 hours) at Ohio State.
Inclusion Criteria:
Exclusion Criteria:
Contact: Michael Di Gregorio | 614-292-0386 | stressandhealth@osu.edu |
United States, Ohio | |
The Ohio State University | Recruiting |
Columbus, Ohio, United States, 43210 |
Principal Investigator: | Janice K. Kiecolt-Glaser | Ohio State University |
Responsible Party: | Ohio State University College of Medicine ( Janice Kiecolt-Glaser, PhD ) |
Study ID Numbers: | AG0087, 2006H0054, R01 AG029562 |
Study First Received: | October 10, 2006 |
Last Updated: | September 19, 2008 |
ClinicalTrials.gov Identifier: | NCT00385723 History of Changes |
Health Authority: | United States: Federal Government |
affect inflammation |
Omega 3 Fatty Acid Inflammation |
Pathologic Processes Inflammation |