Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)

This study has been completed.

First Received: September 12, 2005 No Changes Posted

Sponsored by:	Ernst Moritz Arndt University of Greifswald
Information provided by:	Ernst Moritz Arndt University of Greifswald
ClinicalTrials.gov Identifier:	NCT00196456

Purpose

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal patients

Condition	Intervention	Phase
Periodontal Disease	Procedure: photosensitisation	Phase II

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment, Efficacy Study
Official Title:	Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)

Further study details as provided by Ernst Moritz Arndt University of Greifswald:

Primary Outcome Measures:

pocket depth reduction

Secondary Outcome Measures:

attachmentlevel loss

Estimated Enrollment:	60
Study Start Date:	April 2004
Estimated Study Completion Date:	January 2005

Detailed Description:

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal pockets and to assess the reduction of subgingival bacteria. The first step will include the evaluation of the quantity of the light which will activate the photosensitizer in the various niches in the periodontal pocket. The second step will evaluate the distribution of the photosensitizer in the periodontal pocket.

The third step will assess the woundhealing of the the photodynamic therapy compared to conventional periodontal therapy with an ultrasonic device.

Eligibility

Ages Eligible for Study:	35 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

systemic healthy
>15 teeth
≤ 6 mm >2 teeth
age > 35 years

Exclusion Criteria:

- systemic ill
cardiac pacemaker
< 15 teeth

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00196456

Locations

Germany, Mecklenburg-Vorpommern
Ernst-Moritz-Arndt-Universität Greifswald
Greifswald, Mecklenburg-Vorpommern, Germany, 17489

Sponsors and Collaborators

Ernst Moritz Arndt University of Greifswald

Investigators

Principal Investigator:

Thomas Kocher, Prof.Dr.

Ernst-Moritz-Arndt University Greifswald

More Information

Publications:

Komerik N, Wilson M, Poole S. The effect of photodynamic action on two virulence factors of gram-negative bacteria. Photochem Photobiol. 2000 Nov;72(5):676-80.

Study ID Numbers:	III UV 06/04
Study First Received:	September 12, 2005
Last Updated:	September 12, 2005
ClinicalTrials.gov Identifier:	NCT00196456 History of Changes
Health Authority:	Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Ernst Moritz Arndt University of Greifswald:

Photodynamic lasertherapy
Periodontol disease

Study placed in the following topic categories:

Mouth Diseases
Periodontal Diseases
Stomatognathic Diseases

Additional relevant MeSH terms:

Mouth Diseases
Periodontal Diseases
Stomatognathic Diseases

ClinicalTrials.gov processed this record on September 03, 2009