Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
GlaxoSmithKline |
---|---|
Information provided by: | GlaxoSmithKline |
ClinicalTrials.gov Identifier: | NCT00404274 |
GW679769 may affect liver enzymes that metabolize warfarin. This study is designed to test the extent of the GW679769 affect on Warfarin levels in humans.
Condition | Intervention | Phase |
---|---|---|
Healthy Subjects |
Drug: Casopitant (GW679769) oral tablets Drug: Warfarin oral tablets |
Phase I |
Study Type: | Interventional |
Study Design: | Prevention, Randomized, Open Label, Single Group Assignment, Pharmacokinetics/Dynamics Study |
Official Title: | An Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Steady-State Warfarin When Co-Administered With Repeat Doses of Casopitant [GW679769] in Healthy Adult Subjects. |
Enrollment: | 72 |
Study Start Date: | November 2006 |
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion criteria:
Exclusion criteria:
United States, Florida | |
GSK Investigational Site | |
Gainesville, Florida, United States, 32605 | |
United States, New York | |
GSK Investigational Site | |
Buffalo, New York, United States, 14202 |
Study Director: | GSK Clinical Trials, MD | GlaxoSmithKline |
Responsible Party: | GSK ( Study Director ) |
Study ID Numbers: | NKV105097 |
Study First Received: | November 27, 2006 |
Last Updated: | May 15, 2009 |
ClinicalTrials.gov Identifier: | NCT00404274 History of Changes |
Health Authority: | United States: Food and Drug Administration |
healthy human volunteer casopitant warfarin GW679769 |
Anticoagulants Warfarin Healthy |
Anticoagulants Therapeutic Uses Hematologic Agents Warfarin Pharmacologic Actions |