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Brief Summary

GUIDELINE TITLE

Position statement on routine laboratory testing before endoscopic procedures.

BIBLIOGRAPHIC SOURCE(S)

GUIDELINE STATUS

This is the current release of the guideline.

BRIEF SUMMARY CONTENT

 
RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

 Go to the Complete Summary

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

Definitions for the grades of recommendation (1A to 3) are provided at the end of the "Major Recommendations."

  1. Routine testing to include coagulation studies, chest x-ray films, electrocardiogram (ECG), blood cross-matching, hemoglobin level, urinalysis, and chemistry tests are not recommended before endoscopy. (1C)
  2. All women of child-bearing age should be queried about the possibility of being pregnant. Pregnancy testing may be considered in women of child-bearing age unless there is a history of total hysterectomy, bilateral tubal ligation, or absent menses for 1 year (menopause). (3)
  3. Consider testing based on the perceived level of risk as determined by the medical history and physical examination as follows:
    1. Coagulation studies: Active bleeding, known or clinically suspected bleeding disorder, medication risk (e.g., anticoagulant use, prolonged antibiotics), prolonged biliary obstruction, history of abnormal bleeding (e.g., easy bruisability, epistaxis, bleeding after dental procedures), history of liver disease, malabsorption (e.g., sprue), malnutrition, or other conditions associated with acquired coagulopathies (e.g., leukemia) (3)
    2. Chest x-ray film: Advanced age, significant smoking history, recent upper respiratory tract infection, and severe or decompensated cardiopulmonary disease (3)
    3. ECG: Advanced age and comorbid illness (e.g., heart disease, arrhythmia, diabetes, hypertension, and electrolyte disturbances), particularly for symptomatic patients undergoing more invasive and prolonged procedures (3)
    4. Blood cross-matching: Blood transfusion considered likely (3)
    5. Hemoglobin/hematocrit: Existing anemia, risk factors for bleeding, high risk for adverse events with significant bleeding, advanced liver disease or hematologic disorder, endoscopic procedures associated with a high risk of bleeding complications (3)
    6. Urinalysis: There are no clear indications for obtaining a urinalysis before endoscopy. (1C)
    7. Chemistry testing: Significant endocrine, renal, or hepatic dysfunction and when taking medications that may further impair function (3)

Definitions:

Grade of Recommendation Clarity of Benefit Methodologic Strength Supporting Evidence Implications
1A Clear Randomized trials without important limitations Strong recommendation; can be applied to most clinical settings
1B Clear Randomized trials with important limitations (inconsistent results, nonfatal methodologic flaws) Strong recommendation; likely to apply to most practice settings
1C+ Clear Overwhelming evidence from observational studies Strong recommendation; can apply to most practice settings in most situations
1C Clear Observational studies Intermediate-strength recommendation; may change when stronger evidence is available
2A Unclear Randomized trials without important limitations Intermediate-strength recommendation; best action may differ, depending on circumstances or patients' or societal values
2B Unclear Randomized trials with important limitations (inconsistent results, nonfatal methodologic flaws) Weak recommendation; alternative approaches may be better under some circumstances
2C Unclear Observational studies Very weak recommendation; alternative approaches likely to be better under some circumstances
3 Unclear Expert opinion only Weak recommendation; likely to change as data become available

Adapted from Guyatt G, Sinclair J, Cook D, et al. Moving from evidence to action: grading recommendations—a qualitative approach. In: Guyatt G, Rennie D, editors. Users' guides to the medical literature. Chicago: AMA Press; 2002. p. 599-608.

CLINICAL ALGORITHM(S)

None provided

EVIDENCE SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

The type of supporting evidence is identified and graded for each recommendation (see "Major Recommendations").

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

2008 Nov

GUIDELINE DEVELOPER(S)

American Society for Gastrointestinal Endoscopy - Medical Specialty Society

SOURCE(S) OF FUNDING

American Society for Gastrointestinal Endoscopy

GUIDELINE COMMITTEE

Standards of Practice Committee

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Committee Members: Michael J. Levy, MD; Michelle A. Anderson, MD; Todd H. Baron, MD, Chair; Subhas Banerjee, MD; Jason A. Dominitz, MD, MHS; S. Ian Gan, MD; M. Edwyn Harrison, MD; Steven O. Ikenberry, MD; Sanjay Jagannath, MD; David Lichtenstein, MD; Bo Shen, MD; Robert D. Fanelli, MD, SAGES Representative; Leslie Stewart, RN, SGNA Representative; Khalid Khan, MD, NAPSGHAN Representative

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

Not stated

ENDORSER(S)

Society of American Gastrointestinal and Endoscopic Surgeons - Medical Specialty Society

GUIDELINE STATUS

This is the current release of the guideline.

GUIDELINE AVAILABILITY

Electronic copies: Available from the American Society for Gastrointestinal Endoscopy Web site.

Print copies: Available from the American Society for Gastrointestinal Endoscopy, 1520 Kensington Road, Suite 202, Oak Brook, IL 60523

AVAILABILITY OF COMPANION DOCUMENTS

None available

PATIENT RESOURCES

None available

NGC STATUS

This NGC summary was completed by ECRI Institute on June 12, 2009.

COPYRIGHT STATEMENT

This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions.

DISCLAIMER

NGC DISCLAIMER

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