Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsors and Collaborators: |
University of Alberta Alberta Heritage Foundation for Medical Research Institute of Health Economics |
---|---|
Information provided by: | University of Alberta |
ClinicalTrials.gov Identifier: | NCT00175279 |
BACKGROUND: Although much has been written about the influence of local opinion leaders on clinical practice, there have been few controlled studies of their effect, and almost none have attempted to change prescribing in the community for chronic conditions such as congestive heart failure (CHF) or ischemic heart disease (IHD).
These two conditions are common and there is very good evidence about how to best prevent morbidity and mortality
HYPOTHESIS: An intervention that consists of patient-specific one-page evidence summaries, generated and then endorsed by local opinion leaders, will be able to change prescribing practices of community-based primary care physicians.
DESIGN: A single centre randomized controlled trial comparing an opinion leader intervention to usual care.
Based on random allocation of all physicians in one large Canadian health region, patients with CHF or IHD (not receiving ACE inhibitors or statins, respectively) recruited from community pharmacies will be allocated to intervention or usual care. The primary outcome is improvement in prescription of proven efficacious therapies for CHF (ACE inhibitors) or IHD (statins) within 6 months of the intervention.
Condition | Intervention |
---|---|
Coronary Disease Ischemic Heart Disease Heart Failure |
Behavioral: Opinion leader generated and endorsed evidence summaries |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Safety/Efficacy Study |
Official Title: | A Cluster Randomized Trial to Assess the Impact of Opinion Leader Endorsed Evidence Summaries on Improving Quality of Prescribing for Patients With Chronic Cardiovascular Disease |
Estimated Enrollment: | 160 |
Study Start Date: | January 2002 |
Estimated Study Completion Date: | April 2005 |
BACKGROUND: Although much has been written about the influence of local opinion leaders on clinical practice, there have been few controlled studies of their effect, and almost none have attempted to change prescribing in the community for chronic conditions such as congestive heart failure (CHF) or ischemic heart disease (IHD).
These two conditions are common and there is very good evidence about how to best prevent morbidity and mortality
HYPOTHESIS: An intervention that consists of patient-specific one-page evidence summaries, generated and then endorsed by local opinion leaders, will be able to change prescribing practices of community-based primary care physicians.
DESIGN: A single centre randomized controlled trial comparing an opinion leader intervention to usual care.
Based on random allocation of all physicians in one large Canadian health region, patients with CHF or IHD (not receiving ACE inhibitors or statins, respectively) recruited from community pharmacies will be allocated to intervention or usual care. The primary outcome is improvement in prescription of proven efficacious therapies for CHF (ACE inhibitors) or IHD (statins) within 6 months of the intervention.
Ages Eligible for Study: | 50 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Canada, Alberta | |
University of Alberta | |
Edmonton, Alberta, Canada, T6G 2B7 |
Principal Investigator: | Sumit R Majumdar, MD, MPH | University of Alberta |
Study ID Numbers: | ISRCTN26365328, IHE#102 |
Study First Received: | September 10, 2005 |
Last Updated: | September 10, 2005 |
ClinicalTrials.gov Identifier: | NCT00175279 History of Changes |
Health Authority: | Canada: Health Canada |
coronary disease heart failure quality improvement knowledge translation opinion leaders |
Arterial Occlusive Diseases Coronary Disease Heart Failure Heart Diseases Myocardial Ischemia |
Vascular Diseases Arteriosclerosis Ischemia Coronary Artery Disease |
Arterial Occlusive Diseases Coronary Disease Heart Failure Heart Diseases Myocardial Ischemia |
Vascular Diseases Cardiovascular Diseases Arteriosclerosis Coronary Artery Disease |