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Sponsored by: |
University of Aarhus |
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Information provided by: | University of Aarhus |
ClinicalTrials.gov Identifier: | NCT00424957 |
The purpose of the current study is to look into the pathogenesis of a severe medical condition causing acute episodes on the central nervous system as seen in majority of patients with liver cirrhosis.
Condition |
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Cirrhosis Hepatic Encephalopathy |
Study Type: | Observational |
Study Design: | Case Control, Cross-Sectional |
Official Title: | Brain Energy Metabolism in Patients With Acute Hepatic Encephalopathy Measured With PET |
Ages Eligible for Study: | 45 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
6 patients with liver cirrhosis with an acute episode of hepatic encephalopathy, 6 patients with liver cirrhosis without an acute episode of hepatic encephalopathy, 6 healthy subjects age and sex matched
Inclusion Criteria:
Exclusion Criteria:
Denmark | |
PET Centre, Aarhus University Hospital | |
Aarhus, Denmark, 8000 |
Study Chair: | Susanne Keiding, MD | PET Centre and Medical department V, Aarhus Sygehus, Aarhus University Hospital |
Responsible Party: | PET Center, Aarhus University Hospital ( Peter Iversen ) |
Study ID Numbers: | 20060120 |
Study First Received: | January 19, 2007 |
Last Updated: | February 4, 2009 |
ClinicalTrials.gov Identifier: | NCT00424957 History of Changes |
Health Authority: | Denmark: Ethics Committee; Denmark: The Danish National Committee on Biomedical Research Ethics; Denmark: Danish Dataprotection Agency |
Ammonia Astrocytes Citric acid cycle Alpha ketoglutarate dehydrogenase |
Liver Failure Liver Diseases Metabolic Diseases Fibrosis Citric Acid Central Nervous System Diseases Liver Cirrhosis |
Brain Diseases Hepatic Encephalopathy Digestive System Diseases Citrate Metabolic Disorder Hepatic Insufficiency Brain Diseases, Metabolic |
Liver Failure Liver Diseases Hepatic Encephalopathy Pathologic Processes Metabolic Diseases Digestive System Diseases |
Fibrosis Nervous System Diseases Central Nervous System Diseases Brain Diseases Brain Diseases, Metabolic Hepatic Insufficiency |