Inclusion Criteria

Concurrent Medication:

Allowed:

• Antiviral medication.

Patients must have:

• HIV infection.
• CD4 count >= 50 cells/mm3.
• Recurrent sinusitis.
• No active opportunistic infection.
• No disease progression.

Exclusion Criteria

Co-existing Condition:

Patients with the following symptoms or conditions are excluded:

• Active infection with fever > 102 F.
• Neurological symptoms such as epidural abscess, subdural hematoma, meningitis, and dementia.
• Malignant neoplasm of nasal passages.
• Not expected to remain clinically stable for the next 6 months.
• Inability to comply with protocol requirements.
• Malabsorption or inability to take oral medication.
• Concurrent participation on another study where antibiotics will be used.

Concurrent Medication:

Excluded:

• Antibiotics other than Septra.

Concurrent Treatment:

Excluded:

• Chinese herbal medicine or acupuncture unless on that study arm.
• Surgical intervention that has abated symptoms.

Patients with the following prior condition are excluded:

History of allergic reaction to the study antibiotics.