Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
UPECLIN HC FM Botucatu Unesp |
---|---|
Information provided by: | UPECLIN HC FM Botucatu Unesp |
ClinicalTrials.gov Identifier: | NCT00780364 |
The objective is to establish the effect of sour taste and cold temperature on the pharyngeal swallowing transit time after ischemic hemisphere stroke.
Condition |
---|
Stroke |
Study Type: | Observational |
Study Design: | Cohort, Prospective |
Official Title: | Sour Taste and Cold Temperature Effects on Pharyngeal Transit Time After Ischemic Stroke:Anatomic and Functional Bases. |
Estimated Enrollment: | 30 |
Study Start Date: | March 2008 |
Estimated Study Completion Date: | July 2009 |
Over the past decade there were many studies over normal and pathological swallowing that discuss the influence of taste and temperature. Nevertheless there were many questions on the issue that remains to be solved, including the hemispheric lateralization of lesions dysphagic patients remains also to be fully understood.Swallowing disorder is defined as oropharyngeal dysphagia in presence of alterations in any phase of the complex swallowing dynamics. It could be congenital or acquired, affecting nutritional aspects, hydration, lung function and the individual's social integration [1]. Stroke, has a high incidence among neurological diseases, and cause disturbs on swallowing dynamics presenting signs of dysphagia in at least 50% of cases.A study that analyzed swallowing dynamics by videofluoroscopy in individuals with history of one or more stroke episodes with oropharyngeal dysphagia shows shorter pharyngeal and oropharyngeal transit times with cold stimulus than without them. Other study of heterogeneous neurological diseases such as cerebral palsy, brain trauma, stroke, and Alzheimer's disease, concluded that sour taste improved swallowing, minimizing laryngotracheal penetration and aspiration in individuals with neurological damaged. Chen et al. in an analysis of 42 healthy individuals with several taste bolus found that awareness and arousal could also influence the swallowing function.
Ages Eligible for Study: | 50 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
patients in hospital
Inclusion Criteria:
Exclusion Criteria:
Contact: paula c cola | 55 14 34334128 | paccola@hotmail.com |
Brazil, Sao Paulo | |
Sao Paulo State University | Recruiting |
Botucatu, Sao Paulo, Brazil, 18618-970 | |
Contact: Paula C Cola 55 14 34334128 paccola@hotmail.com |
Principal Investigator: | Paula C Cola, master | Sao Paulo State University |
Responsible Party: | Individual ( Paula Cristina Cola ) |
Study ID Numbers: | upeclin/HC/FMB-Unesp-18 |
Study First Received: | October 24, 2008 |
Last Updated: | June 3, 2009 |
ClinicalTrials.gov Identifier: | NCT00780364 History of Changes |
Health Authority: | Brazil: National Committee of Ethics in Research |
stroke; sour taste; cold temperature; pharyngeal swallowing |
Deglutition Disorders Cerebral Infarction Stroke Vascular Diseases |
Central Nervous System Diseases Ischemia Brain Diseases Cerebrovascular Disorders |
Nervous System Diseases Stroke Vascular Diseases Central Nervous System Diseases |
Cardiovascular Diseases Brain Diseases Cerebrovascular Disorders |