Stevens-Johnson Syndrome Antimicrobial - Full Text View

Sponsored by:	University of Pernambuco
Information provided by:	University of Pernambuco
ClinicalTrials.gov Identifier:	NCT00844038

Purpose

Steven-Johnson's syndrome, or great multiform erythema, appears as a systemic disturbance, with skin involvement and mucous membranes, related to several factors, such as, viral or bacterial infections and mainly the administration of medicines, in general painkillers and antibiotics. The objective of this work is report the emergence of ulcerative vesicle -bubble chronic disease in areas of lips, gum, tongue and genital mucous membrane in a 26 year-old patient, leucoderma and masculine gender, in treatment of breathing infection with sulfametoxazol-trimetropima, having been diagnosed as syndrome of Steven-Johnson.

Condition
Stevens-Johnson Syndrome

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Stevens-Johnson Syndrome Associated With Antimicrobial

Further study details as provided by University of Pernambuco:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	1
Study Start Date:	August 2008
Study Completion Date:	December 2008
Primary Completion Date:	August 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Sick

Detailed Description:

Among the serious medicaments reactions, there are as great representative the Mucocutaneous Disorders immunological mediated. Steven-Johnson's syndrome, or great multiform erythema, appears as a systemic disturbance, with skin involvement and mucous membranes, related to several factors, such as, viral or bacterial infections and mainly the administration of medicines, in general painkillers and antibiotics. The objective of this work is report the emergence of ulcerative vesicle -bubble chronic disease in areas of lips, gum, tongue and genital mucous membrane in a 26 year-old patient, leucoderma and masculine gender, in treatment of breathing infection with sulfametoxazol-trimetropima, having been diagnosed as syndrome of Steven-Johnson.

Eligibility

Ages Eligible for Study:	20 Years to 60 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

1

Criteria

Inclusion Criteria:

Stevens-Johnson syndrome associated with antimicrobial

Exclusion Criteria:

Not sick

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00844038

Locations

Brazil, Pernambuco
University of Pernambuco
Recife, Pernambuco, Brazil, 52021220

Sponsors and Collaborators

University of Pernambuco

Investigators

Principal Investigator:

Edwaldo Dr Dourado, Doctor

University of Pernambuco

More Information

Publications:

Vanfleteren I, Van Gysel D, De Brandt C. Stevens-Johnson syndrome: a diagnostic challenge in the absence of skin lesions. Pediatr Dermatol. 2003 Jan-Feb;20(1):52-6.

Responsible Party:	University of Pernambuco ( Stevens-Johnson syndrome associated with antimicrobial )
Study ID Numbers:	SSJ1, 558187121279
Study First Received:	February 12, 2009
Last Updated:	February 12, 2009
ClinicalTrials.gov Identifier:	NCT00844038 History of Changes
Health Authority:	Brazil: Ethics Committee

Keywords provided by University of Pernambuco:

Steven-Johnson syndrome
erythema multiform
autoimmune disease

Study placed in the following topic categories:

Mouth Diseases
Anti-Infective Agents
Erythema
Autoimmune Diseases
Skin Diseases, Vesiculobullous

Skin Diseases
Stomatitis
Stevens-Johnson Syndrome
Stomatognathic Diseases

Additional relevant MeSH terms:

Mouth Diseases
Anti-Infective Agents
Erythema
Disease
Stomatitis
Skin Diseases
Skin Diseases, Vesiculobullous

Pharmacologic Actions
Pathologic Processes
Syndrome
Therapeutic Uses
Stevens-Johnson Syndrome
Erythema Multiforme
Stomatognathic Diseases

ClinicalTrials.gov processed this record on September 01, 2009