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Sponsors and Collaborators: |
Stanford University Duke University GlaxoSmithKline |
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Information provided by: | Stanford University |
ClinicalTrials.gov Identifier: | NCT00285727 |
This is an 8 week study for patients who are currently taking antidepressant medication but not fully responding.
Ropinirole CR would be taken in conjunction with current antidepressant medication. Patients come into the clinic once a week when starting on the medication and then once every other week for the remainder of the 8 weeks.
Condition | Intervention |
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Depressive Disorder, Major |
Drug: Ropinirole CR |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Active Control, Single Group Assignment, Safety/Efficacy Study |
Official Title: | Ropinirole Controlled Release (CR) as an Adjunctive Agent in the Treatment of Major Depression |
Estimated Enrollment: | 60 |
Study Start Date: | January 2006 |
Estimated Study Completion Date: | October 2007 |
We hope to learn whether ropinirole CR (controlled release formulation) is safe and effective when taken with an antidepressant to reduce the symptoms of depression. Adults who have a diagnosis of major depression and are currently taking an adequate dose of antidepressant medication will be sought for participation. They will continue to take the antidepressant medication and will receive ropinirole CR, an investigational medication, for eight weeks during which information will be collected about mood and cognitive functioning.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
United States, California | |
Depression Research Clinic, Psychiatry Department, Stanford School of Medicine | |
Stanford, California, United States, 9430 | |
Stanford University School of Medicine | |
Stanford, California, United States, 94305 |
Principal Investigator: | Charles Debattista | Depression Research Clinic, Psychiatry Department, Stanford School of Medicine |
Study ID Numbers: | 2969 |
Study First Received: | January 31, 2006 |
Last Updated: | May 16, 2008 |
ClinicalTrials.gov Identifier: | NCT00285727 History of Changes |
Health Authority: | United States: Food and Drug Administration |
Neurotransmitter Agents Ropinirole Dopamine Depression Mental Disorders Mood Disorders |
Dopamine Agents Depressive Disorder, Major Dopamine Agonists Depressive Disorder Behavioral Symptoms |
Neurotransmitter Agents Ropinirole Depression Molecular Mechanisms of Pharmacological Action Anti-Dyskinesia Agents Physiological Effects of Drugs Antiparkinson Agents Depressive Disorder, Major Depressive Disorder |
Dopamine Agonists Pharmacologic Actions Behavioral Symptoms Mental Disorders Therapeutic Uses Mood Disorders Dopamine Agents Central Nervous System Agents |