NIDA is urgently seeking SBIR grant applications for development of diagnostic kits for rapid detection of gamma-hydroxy butyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butane-diol (BD) in body fluids (plasma or urine). These three substances are often called by their group-name, GHB, and they are metabolically linked. GHB poisoning results in coma and may result and death. The kits are needed to assist emergency room doctors in rapid diagnosis of GHB poisoning, which is very difficult and critical for selection of proper treatment strategy. The method of detection should be quick, qualitative, and specific and measure GHB concentrations above its endogenous levels.

Interested applicants please contact:

Dr. Hari Singh (301) 443-6300.