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"Current Issues in Cigarette Smoking and HIV/AIDS" Workshop |
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Natcher Conference Center, NIH
NIDA Organizer(s): Meeting Purpose and Intent:The purpose of this workshop was to highlight understudied issues related to cigarette smoking in HIV-infected persons. In the U.S., the prevalence of cigarette smoking is estimated to be 50-70% among HIV-infected persons and 75% among substance abusers, compared to 25% in the general population. Smoking is associated with reduced health-related quality of life in HIV-infected persons, increased incidence of bacterial pneumonia and other AIDS defining illnesses, increase incidence of malignancies, and increased mortality risk compared to HIV+ non-smokers. Indeed, emerging evidence suggests that tobacco smoking may actually be an independent risk factor for HIV infection. Some studies also suggest that nicotine smoking may be associated with faster progression to AIDS and/or neurological complications of AIDS. Furthermore, smokers taking Highly Active Antiretroviral Therapy (HAART) are at increased risk for lipodystrophy and cardiac disease compared to non-smokers. New data also suggests that women smokers on HAART have poorer viral responses, poorer immunologic response, greater risk of virologic rebound, more frequent immunologic failure, and have higher risk of developing AIDS. Presentations and Workshop Activities:
The presenters and invited attendees participated in afternoon breakout groups on "Disease Mechanisms", "Treatment" or "Epidemiology/Population". Each group discussed where the largest gaps were, and what the top research priorities should be. Questions that were addressed included:
Meeting Outcome:A special, peer-reviewed supplement of AIDS Education and Prevention: An Interdisciplinary Journal is anticipated to be published in March/April 2008. Submissions will be by invitation only and will be based on several areas of interest that follow directly from this workshop, including:
This supplement will continue the partnership between NIDA, NCI, FIC, NCMHD and NIAID. |
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