Overview

The NIH Roadmap is an innovative approach to accelerate fundamental discovery and translation of that knowledge into effective prevention strategies and new treatments. The strategic initiatives to be funded under the NIH Roadmap will address critical roadblocks and knowledge gaps that currently constrain rapid progress in biomedical research. They will synergize the work of many NIH Institutes and Centers, and collectively represent a unique effort that no single or group of Institutes or Centers or other entity can do, but are the responsibility of the NIH as a whole.

Three broad initiatives will be stimulated with these funds:

• New Pathways to Discovery, which includes a comprehensive understanding of building blocks of the body's cells and tissues and how complex biological systems operate; structural biology; molecular libraries and imaging; nanotechnology; bioinformatics and computational biology;
• Research Teams of the Future, including interdisciplinary research, high-risk research, and public-private partnerships
• Re-engineering the Clinical Research Enterprise. Through these efforts, NIH will boost the resources and technologies needed for 21st century biomedical science

Latest Funding Opportunity Announcements

• The NIH Common Fund has received additional funds through the American Recovery & Reinvestment Act of 2009 (Recovery Act; Pub. L. No. 111-5) and is supporting several new funding opportunities. NIH Roadmap program areas will be among the priority areas for the ARRA Common Funds. More about the NIH Common Fund...
• RFA: Genotype-Tissue Expression (GTEx) - Laboratory, Data Analysis and Coordinating Center (LDACC) - Response Date: Sep 11, 2009
• RFA: Pilot-Scale Libraries (PSL) for High-Throughput Screening (P41) - Expiration Date: October 2, 2009
• Notice: Correction to Award Information for PAR-08-024 Assay Development for High Throughput Molecular Screening
• Notice of Opportunity for Fast Track Entry of Assay Projects for High Throughput Screening into the NIH Roadmap Molecular Libraries Probe Production Centers Network
• RFA: Novel statistical methods for human gene expression quantitative trait loci (eQTL) analysis (R01) - Expiration Date: September 17, 2009.
• PAR: Solicitation of Assays for High Throughput Screening (HTS) in the Molecular Libraries Probe Production Centers Network (MLPCN) (R03)

Recently Expired Announcements

• Notice: Request for Information: Nomination of Monoclonal Antibody Targets for Epigenetic Research
• Notice: Request for Information (RFI): Soliciting Input on Current Needs in the NIH Roadmap Molecular Libraries and Imaging Initiative
• RFA: 2009 NIH Directors Pioneer Award Program (DP1)
• RFA: 2009 NIH Directors New Innovator Award Program (DP2)
• PAR: Pre-Application for the 2009 NIH Director's Pioneer Award Program (X02)
• PAR: Pre-Application for the 2009 NIH Director's New Innovator Award Program (X02)

622507 since 12/23/03