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Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)
This study is ongoing, but not recruiting participants.
First Received: August 12, 2008   No Changes Posted
Sponsored by: Imperial College London
Information provided by: Imperial College London
ClinicalTrials.gov Identifier: NCT00733759
  Purpose

Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations. Patients with PAVMs have usually have low blood oxygen levels and are at risk of other complications including strokes, brain abscesses, pregnancy-related complications and haemorrhage. We hypothesise that the complications of PAVM patients arise from their PAVMs and not the more recognised intracardiac forms of shunting. We propose to perform echocardiograms to enable assessment of the presence of other causes of capillary-free communications between the pulmonary and systemic circulations.


Condition
Pulmonary Arteriovenous Malformations

Study Type: Observational
Study Design: Prospective
Official Title: The Evaluation of Intra-Cardiac Shunts in Patients With Pulmonary Arteriovenous Malformations

Resource links provided by NLM:


Further study details as provided by Imperial College London:

Estimated Enrollment: 45
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • patients with pulmonary arteriovenous malformations (PAVMs)

Exclusion Criteria:

  • unable to provide informed consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00733759

Locations
United Kingdom
Imperial College Hammersmith Campus
London, United Kingdom, W12 0NN
Sponsors and Collaborators
Imperial College London
Investigators
Principal Investigator: Claire L Shovlin Imperial College London
  More Information

No publications provided

Study ID Numbers: IC/CLS10
Study First Received: August 12, 2008
Last Updated: August 12, 2008
ClinicalTrials.gov Identifier: NCT00733759     History of Changes
Health Authority: United Kingdom: Research Ethics Committee

Study placed in the following topic categories:
Pulmonary Arteriovenous Malformation
Cardiovascular Abnormalities
Aneurysm
Vascular Malformations
Vascular Diseases
Hemangioma
Arteriovenous Malformations
Congenital Abnormalities

Additional relevant MeSH terms:
Neoplasms
Neoplasms by Histologic Type
Cardiovascular Abnormalities
Aneurysm
Vascular Malformations
Neoplasms, Vascular Tissue
Vascular Diseases
Hemangioma
Cardiovascular Diseases
Arteriovenous Malformations
Congenital Abnormalities

ClinicalTrials.gov processed this record on August 26, 2009