The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR

This study is currently recruiting participants.

Verified by University of Roma La Sapienza, May 2007

First Received: May 7, 2007 No Changes Posted

Sponsored by:	University of Roma La Sapienza
Information provided by:	University of Roma La Sapienza
ClinicalTrials.gov Identifier:	NCT00470769

Purpose

It is generally assumed that renal blood flow is symmetric in the absence of renal artery stenosis. The importance of studying the function of both kidneys separately is because it cannot be assumed that they are functionally equal.The aim of the present study is to evaluate whether this is really in patients with essential hypertension and/or moderate kidneys loss.

Condition	Intervention
Hypertension Renal Failure	Procedure: Color-Doppler Ultrasound, 99mTc-DTPA scintigraphy

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title:	Color-Doppler Ultrasonography vs 99mTc-DTPA Scintigraphy to Assess the Renal Blood Flow

Resource links provided by NLM:

MedlinePlus related topics: High Blood Pressure Kidney Failure Nuclear Scans Ultrasound

U.S. FDA Resources

Further study details as provided by University of Roma La Sapienza:

Estimated Enrollment:	2006
Study Start Date:	September 2006
Estimated Study Completion Date:	May 2007

Detailed Description:

To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we comparing left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by 99mTc-DTPA scintigraphy in 50 patients with hypertension and/or moderate renal failure, compared with 30 normal control subjects.

Eligibility

Ages Eligible for Study:	30 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Patients with hypertension
Patients with moderate renal insufficiency
Normal subjects

Exclusion Criteria:

Patients with solitary kidney function
Patients with renal artery stenosis
Patients underwent renal angioplasty and stenting

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00470769

Contacts

Contact: Rosario Cianci, MD

+39335206441

ciancirosario@tin.it

Locations

Italy
University of Rome La Sapienza	Recruiting
Roma, Italy, 00100
Contact: Rosario Cianci, MD +39335206441 ciancirosario@tin.it
Contact: Giorgio Fuiano, MD +39 0961775360 gfuiano@libero.it
Giorgio Fuiano	Recruiting
Catanzaro, Italy, 88020
Rosario Cianci	Recruiting
Rome, Italy, 00100

Sponsors and Collaborators

University of Roma La Sapienza

Investigators

Principal Investigator:	Rosario Cianci, MD	Department Of Clinic Medicine, Chair of Nephrology
Study Director:	Giorgio Fuiano, MD	University of Catanzaro

More Information

No publications provided

Study ID Numbers:	CR-UR-00001
Study First Received:	May 7, 2007
Last Updated:	May 7, 2007
ClinicalTrials.gov Identifier:	NCT00470769 History of Changes
Health Authority:	Italy: National Bioethics Committee

Keywords provided by University of Roma La Sapienza:

Color-Doppler Ultrasonography
Renal scintigraphy
Kidney failure
GFR

Study placed in the following topic categories:

Renal Insufficiency
Urologic Diseases
Vascular Diseases

Kidney Diseases
Hypertension
Kidney Failure

Additional relevant MeSH terms:

Renal Insufficiency
Urologic Diseases
Vascular Diseases
Cardiovascular Diseases

Kidney Diseases
Kidney Failure
Hypertension

ClinicalTrials.gov processed this record on August 13, 2009