AGENDA

Workshop on Interventions for Metabolic and Endocrine Complications of HIV/AIDS and Drug Abuse
November 26-27, 2001

Co-sponsored by
• National Institute on Drug Abuse (NIDA)
• Office of Dietary Supplements (ODS)
• National Center for Complementary and Alternative Medicine (NCCAM)
• National Institutes of Health

Natcher Building (Conference Room D), NIH Campus Bethesda, Maryland

Time	Event
8:00-8:30 a.m.	Registration/Continental Breakfast
8:30-8:40 a.m.	Welcome Jag H. Khalsa, Ph.D. and Paul Coulis, Ph.D. Center on AIDS and Other Medical Consequences of Drug Abuse (CAMCODA)
8:40-8:50 a.m.	Introduction Sander Genser, M.D., M.P.H., Head Medical Consequences Unit, CAMCODA Henry Francis, M.D., Director, CAMCODA
8:50-9:00 a.m.	Opening Remarks Richard Millstein, Deputy Director, NIDA
9:00-9:10 a.m.	The Mission of the Office of Dietary Supplements Paul Coates, Ph.D., Director, ODS
9:10-9:20 a.m.	Missions and Goals of the National Center for Complementary and Alternative Medicine (NCCAM) Steven Straus, M.D., Director, NCCAM
Metabolic Complications of HIV/AIDS & Drug Abuse Chair: Sherwood Gorbach, M.D., Professor, Tufts University Co-Chair: Donald Kotler, M.D., Professor, Columbia University
9:20-9:25 a.m.	Introduction Sherwood Gorbach, M.D., Professor, Tufts University
9:25-9:55 a.m.	Difficulties in Understanding Metabolic Complications of HIV/AIDS Carl Grunfeld, M.D., Ph.D., Professor, University of California, San Francisco
9:55-10:20 a.m.	Break
10:20-10:50 a.m.	Adipocyte Biology and Lipodystrophy Donald Kotler, M.D., Professor, Columbia University
10:50-11:00 a.m.	Break
11:00-11:30 a.m.	Turnover of Adipocytes and Mitochondrial DNA in Humans: Direct Testing of Pathogenic Role in Lipodystrophy and Mitochondrial Toxicity Syndromes Marc Hellerstein, M.D., Ph.D., Professor, University of California, San Francisco
11:30 a.m.-12:00 p.m.	Does Fat Mass Protect Women with HIV from HIV Progression or CD4 Cell Decline? Clara Jones, M.D., M.P.H., Assistant Professor, Tufts University
12:00-12:30 p.m.	Discussion
12:30-1:30 p.m.	Lunch On Your Own
1:30-2:00 p.m.	Opportunistic Illnesses and Metabolic Complications of HIV/AIDS Christine Wanke, M.D., Associate Professor, Tufts University
2:00-2:30 p.m.	Mechanisms and Strategies for Insulin Resistance in HIV Disease Steve Grinspoon, M.D., Assistant Professor, Harvard University
2:30-3:00 p.m.	Bone Disorders in HIV Infection Marshall Glesby, M.D., Ph.D., Assistant Professor, Weill Medical College/Cornell University
3:00-3:30 p.m.	Discussion
3:15-3:30 p.m.	Break
Interventions for Metabolic Complications: Chair: Richard Semba, M.D., M.P.H., Associate Professor, The Johns Hopkins University Co-Chair: Abby Shevitz, M.D., Assistant Professor, Tufts University
3:30-4:00 p.m.	Interventions for Visceral Adipocity Associated with HIV/AIDS Ellen Engelson, Ed.D, Associate Research Scientist, Columbia University
4:00-4:30 p.m.	The Effects of Nutrition, Oxandrolone, and Exercise for the Treatment of Wasting from a Randomized Clinical Trial of a Varied Patient Population Abby Shevitz, M.D., M.P.H., Assistant Professor, Tufts University
4:30-5:00 p.m.	Dietary Habits and Metabolic Abnormalities in AIDS Lipodystrophy Colleen Hadigan, M.D., M.P.H., Assistant Professor, Harvard University
5:00-5:30 p.m.	Iron Deficiency Anemia in HIV-Infected and Drug Exposed Women and Children Richard Semba, M.D., M.P.H., Associate Professor, The Johns Hopkins University
5:30-6:00 p.m.	Discussion and Summary of the First Day Richard Semba, M.D., M.P.H.

Tuesday, November 27

8:00-8:30 a.m.	Micronutrients and Health Outcomes Among HIV-infected Women and Children Wafaie Fawzi, M.D., Associate Professor, Harvard University
8:30-9:00 a.m.	Zinc Status in HIV Infection and Drug Abuse Marianna Baum, Ph.D., Professor, Florida International University
9:00-9:30 a.m.	Oxidative Stress and Antioxidant Status in HIV+ and HIV- Injections Drug Users Alice Tang, Ph.D., Assistant Professor, Tufts University
9:30-9:45 a.m.	Discussion
9:45-10:00 a.m.	Break
Endocrine Complications of HIV/AIDS and Drug Abuse and Interventions Chair: Adrian Dobs, M.D., M.H.S., Professor, The Johns Hopkins University Co-Chair: Shally Bhasin, M.D., Professor, University of California, Los Angeles
10:00-10:30 a.m.	Endocrine Complications of HIV Infection and Substance Abuse in Brazil Rosita Fontes, M.D., Professor, Catholic University of Rio de Janeiro
10:30-11:00 a.m.	Endocrine Complications of HIV/AIDS and Substance Abuse, and Interventions: USA Adrian Dobs, M.D., M.H.S., Professor, The Johns Hopkins University
11:00-11:30 a.m.	Testosterone Effects on Regional Fat Deposition, Insulin Sensitivity, and Atherosclerosis Progression Shally Bhasin, M.D., Professor, University of California, Los Angeles
11:30-11:45 a.m.	Break
11:45 a.m.-12:15 p.m.	Metabolic Effects of Growth Hormone Complications in Patients with HIV Infection Kathleen Mulligan, Ph.D., Assistant Professor, University of California, San Francisco
12:15-12:45 p.m.	Alternative Modalities in the Treatment of Endocrine and Metabolic Complications of HIV/AIDS and Drug Abuse Jerome Ernst, M.D., M.S., Director, Community Research Initiative on AIDS, New York
12:45-1:45 p.m.	Discussion and Working Lunch
1:45-2:45 p.m.	Breakout Sessions Group I: Metabolic Complications/Interventions, Open Discussion Moderators: Carl Grunfeld, M.D., Ph.D./Donald Kotler, M.D. (Room D) Group II: Endocrine Complications/Interventions, Open Discussion Moderators: Adrian Dobs, M.D., M.H.S./Shally Bhasin, M.D. (Room F)
2:45-3:45 p.m.	Roundtable Open Panel Discussion and Recommendations for Future Research Moderator: Sherwood Gorbach, M.D. Issues to cover: NIDA Portfolio Future Research
3:45 p.m.	Adjourn