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Nutrigenomics: The Genome–Food Interface M. Nathaniel Mead Abstract Nutrigenomics is the study of how nutrients affect the expression of an individual's genetic makeup-the impact of dietary components on the genome, the proteome (the sum total of all proteins) , and the metabolome (the sum of all metabolites) in humans. Researchers recognize that only a proportion of the population will respond positively to specific nutritional interventions, while a number of people will be unresponsive, and some individuals could even be adversely affected. Nutrigenomicists are therefore looking at how the interface of genes and diet may influence the rising rates of health problems such as cardiovascular disease, diabetes, and obesity in countries around the world. The full version of this article is available for free in HTML or PDF formats. |
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