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Jose Ordovas
(Tufts University)
Human Nutrition Research Center on Aging
(This person is no longer with ARS)
Publications |
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The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican Health Study
- (Peer Reviewed Journal)
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Junyent, M., Tucker, K., Smith, C., Garcia-Rios, A., Mattei, J., Lai, C., Parnell, L.D., Ordovas, J.M. 2008. The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican Health Study. Journal of Lipid Research. 50:565-573.
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Matrix Gla Protein polymorphisms are associated with coronary artery calcification
- (Peer Reviewed Journal)
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Crosier, M.D., Booth, S.L., Peter, I., Dawson-Hughes, B., Price, P.A., O'Donnell, C.J., Hoffman, U., Williamson, M.K., Ordovas, J.M. 2009. Matrix Gla Protein polymorphisms are associated with coronary artery calcification. Journal of Nutritional Science and Vitaminology. 55:59-65.
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Wdtc1, An Ortholog of Drosphilia Adipose Gene, Associates with Human Obesity
- (Peer Reviewed Journal)
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Lai, C., Parnell, L.D., Garcia-Bailo, B., Tucker, K., Ordovas, J.M. 2008. WDTC1, an ortholog of Drosphilia adipose gene, associates with human obesity. Obesity. 17(3):593-600.
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Effects of Perilipin (PLIN) Gene Variation on Metabolic Syndrome Risk and Weight-Loss in Obese Children and Adolescents
- (Peer Reviewed Journal)
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Deram, S., Nicolau, C.Y., Perez-Martinez, P., Guazzelli, I., Halpern, A., Wajchenberg, B.L., Ordovas, J.M., Villares, S.M. 2008. Effects of Perilipin (PLIN) Gene Variation on Metabolic Syndrome Risk and Weight-Loss in Obese Children and Adolescents. Journal of Clinical Endocrinology and Metabolism. 93: 4933 - 4940.
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Adipoq Polymorphisms, Monounsaturated Fatty Acids, and Obesity Risk: the Goldn Study
- (Peer Reviewed Journal)
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Warodomwichit, D., Shen, J., Arnett, D., Tsai, M., Kabagambe, E., Peacock, J., Hixson, J., Straka, R., Province, M., An, P., Lai, C., Parnell, L.D., Borecki, I., Ordovas, J.M. 2009. ADIPOQ Polymorphisms, Monounsaturated Fatty Acids, and Obesity Risk: The GOLDN Study. Obesity. 17:510-517.
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Smoking, inflammatory patterns, and postprandial hypertriglyceridemia
- (Peer Reviewed Journal)
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Kabagambe, E.K., Ordovas, J.M., Tsai, M.Y., Borecki, I.B., Hopkins, P.N., Arnett, D.K. 2009. Smoking, inflammatory patterns, and postprandial hypertriglyceridemia. Atherosclerosis. 203(2):633-639.
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Perilipin Polymorphism Interacts with Dietary Carbohydrates to Modulate Anthropometric Traits in Hispanics of Caribbean Origin
- (Peer Reviewed Journal)
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Smith, C., Tucker, K., Yiannakouris, N., Garcia-Bailo, B., Mattei, J., Lai, C., Parnell, L.D., Ordovas, J.M. 2008. Perilipin Polymorphism Interacts with Dietary Carbohydrates to Modulate Anthropometric Traits in Hispanics of Caribbean Origin. Journal of Nutrition. 138(10):1852-1858.
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Gene¿Environment Interactions and Susceptibility to Metabolic Syndrome and Other Chronic Diseases
- (Review Article)
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Ordovas, J.M., Shen, J. 2008. Gene¿Environment Interactions and Susceptibility to Metabolic Syndrome and Other Chronic Diseases. Journal of Periodontology. 79(8S):1508-1513.
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A Common Missense Variant in the Glucokinase Regulatory Protein Gene (GCKR) Is Associated with Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
- (Peer Reviewed Journal)
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Orho-Melander, M., Melander, O., Guiducci, C., Perez-Martinez, P., Corella, D., Roos, C., Tewhey, R., Rieder, M.J., Hall, J., Abecasis, G., Tai, E., Welch, C., Arnett, D.K., Lyssenko, V., Lindholm, E., Saxena, R., De Bakker, P., Burtt, N., Voight, B.F., Hirschhorn, J.N., Tucker, K., Hedner, T., Tuomi, T., Isomaa, B., Eriksson, K., Taskinen, M., Wahlstrand, B., Hughes, T.E., Parnell, L.D., Lai, C., Berglund, G., Peltonen, L., Vartiainen, E., Jousilahti, P., Havulinna, A.S., Salomaa, V., Nilsson, P., Groop, L., Altshuler, D., Ordovas, J.M., Kathiresan, S. 2008. A Common Missense Variant in the Glucokinase Regulatory Protein Gene (GCKR) Is Associated with Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations. Diabetes. 57:3112-3121.
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The challenges of molecular nutrition research 1- Linking genotype to healthy nutrition
- (Review Article)
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Williams, C.M., Ordovas, J.M., Lairon, D., Hesketh, J., Lietz, G., Gibney, M., Van Ommen, B. 2008. The challenges of molecular nutrition research 1- Linking genotype to healthy nutrition. Genes and Nutrition. 3(2):41¿49.
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Adiponectin Gene Variants are Associated with Insulin Sensitivity in Response to Dietary Fat Consumption in Caucasian Men
- (Peer Reviewed Journal)
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Perez-Martinez, P., Lopez-Miranda, J., Cruz-Teno, C., Delgado-Lista, J., Jimenez-Gomez, Y., Fernandez, J.M., Gomez, M.J., Marin, C., Perez-Jimenez, F., Ordovas, J.M. 2008. Adiponectin Gene Variants are Associated with Insulin Sensitivity in Response to Dietary Fat Consumption in Caucasian Men. Journal of Nutrition. 138(9): 1609-1614.
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Influence of genetic factors in the modulation of postprandial lipemia
- (Review Article)
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Perez-Martinez, P., Lopez-Miranda, J., Perez-Jimenez, F., Ordovas, J.M. 2008. Influence of genetic factors in the modulation of postprandial lipemia. Atherosclerosis Supplements. 9:49-55.
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Vitamin K circulating cytokines and bone mineral density in older men and women
- (Peer Reviewed Journal)
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Shea, K., Dallal, G., Dawson-Hughes, B., Ordovas, J.M., O'Donnell, C., Gundberg, C., Peterson, J., Booth, S.L. 2008. Vitamin K circulating cytokines and bone mineral density in older men and women. American Journal of Clinical Nutrition. 88:356-63.
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The effect of IL6-174C/G polymorphisms on postprandial triglycerides metabolism in the GOLDN study
- (Peer Reviewed Journal)
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Shen, J., Arnett, D.K., Perez-Martinez, P., Parnell, L.D., Peacock, J.M., Hixson, J.E., Tsai, M.Y., Lai, C., Straka, R.J., Hopkins, P.N., Ordovas, J.M. 2008. The effect of IL6-174C/G polymorphisms on postprandial triglycerides metabolism in the GOLDN study. Journal of Lipid Research. 49:1839-1845.
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Clinical significance of apolipoprotein A5
- (Review Article)
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Tai, E., Ordovas, J.M. 2008. Clinical significance of apolipoprotein A5. Current Opinion in Lipidology. 19(4):349-354.
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Associations between vitamin K and circulating cytokines in older men and women
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Shea, K.M., Dallal, G., Dawson-Hughes, B., Ordovas, J.M., O'Donnell, C.J., Gundberg, C., Peterson, J.W., Booth, S.L. 2008. Associations between vitamin K and circulating cytokines in older men and women. FASEB Journal. 22:1106.1
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Association of common C-protein (CRP) gene polymorphism with baseline plasma CRP levels and fenofibrate response: The GOLDN Study
- (Peer Reviewed Journal)
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Shen, J., Arnett, D.K., Parnell, L.D., Peacock, J.M., Lai, C., Hixson, J.E., Tsai, M.Y., Province, M., Straka, R.J., Ordovas, J.M. 2008. Association of common C-protein (CRP) gene polymorphism with baseline plasma CRP levels and fenofibrate response: The GOLDN Study. Diabetes Care. 31(5):910-915.
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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
- (Peer Reviewed Journal)
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Kathiresan, S., Melander, O., Guiducci, C., Surti, A., Burtt, N.P., Rieder, M.J., Cooper, G.M., Roos, C., Voight, B.F., Havulinna, A.S., Wahlstrand, B., Hedner, T., Corella, D., Tai, E.S., Ordovas, J.M., Berglund, G., Vartiainen, E., Jousilahti, P., Hedblad, B., Taskinen, M., Newton-Cheh, C., Salomaa, V., Peltonen, L., Groop, L., Altshuler, D.M., Orho-Melander, M. 2008. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nature Genetics. 40(2):189-197.
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Ppargc1a Variations Associated with DNA Damage, Diabetes, and Cardiovascular Diseases: the Boston Puerto Rican Study
- (Review Article)
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Lai, C., Tucker, K., Parnell, L.D., Adiconis, X., Garcia-Bailo, B., Griffith, J., Meydani, M., Ordovas, J.M. 2008. PPARGC1A Variations Associated with DNA Damage, Diabetes, and Cardiovascular Diseases: The Boston Puerto Rican Study. Diabetes. 57:809-816.
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Genetic Influences on Blood Lipids and Cardiovascular Risk
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Ordovas, J.M. 2008. Genetic Influences on Blood Lipids and Cardiovascular Risk. In: Coulston, A., Boushey, C. Nutrition in the Prevention and Treatment of Disease, 2nd Edition. Elsevier: 485-513.
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The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment
- (Peer Reviewed Journal)
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Ordovas, J.M., Smith, J., Arnett, D., Kelly, R., Sun, Y., Hopkins, P., Hixson, J., Straka, R., Peacock, J., Kardia, S. 2008. The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment. European Journal of Human Genetics. 16(5):603-613.
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Genetic predisposition, non-genetic risk factors and coronary infarct
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Ordovas, J.M., Trichopoulou, A., Yiannakouris, N., Bamia, C., Benetou, V., Trichopoulos, D. 2008. Genetic predisposition, non-genetic risk factors and coronary infarct. Archives of Internal Medicine. 168(8)891-896.
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The APOB -516C/T polymorphism has no effect on lipid and apolipoprotein response following changes in dietary fat intake in a healthy population
- (Peer Reviewed Journal)
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Perez-Martinez, P., Perez-Jimenez, F., Ordovas, J.M., Bellido, C., Moreno, J.A., Gomez, P., Marin, C., Frenandez De La Puebla, R.A., Paniagua, J.A., Lopez-Miranda, J. 2007. The APOB -516C/T polymorphism has no effect on lipid and apolipoprotein response following changes in dietary fat intake in a healthy population. Nutrition Metabolism and Cardiovascular Disease. 17(3):224-229.
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Red blood cell fatty acid composition and the metabolic syndrome: NHLBI GOLDN study
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Ordovas, J.M., Kabagambe, E., Tsai, M., Arnett, D., Peacock, J., Hopkins, P., Borecki, I., Hixson, J. 2008. Red blood cell fatty acid composition and the metabolic syndrome: NHLBI GOLDN study. Clinical Chemistry. 54(1):154-162.
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Genotype-phenotype associations: Modulation by diet and obesity
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Ordovas, J.M. 2008. Genotype-phenotype associations: Modulation by diet and obesity. Obesity. 16:S40-S46.
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Folic acid, homocysteine and cardiovascular disease: Are the dots connecting?
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Ordovas, J.M. 2008. Folic acid, homocysteine and cardiovascular disease: Are the dots connecting?. Current Cardiovascular Risk Reports. 2(1):7-8.
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Gender, a Significant Factor in the Cross Talk Between Genes, Environment, and Health
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Ordovas, J.M. 2007. Gender, a Significant Factor in the Cross Talk Between Genes, Environment, and Health. Principles of Gender-specific Medicine. 4(B): S111-22.
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Postprandial Triglyceride Metabolism is Modified by the Presence of Genetic Variation at the Perilipin (PLIN) Locus in Two Caucasian Populations
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Perez-Martinez, P., Yiannakouris, N., Lopez Miranda, J., Arnett, D., Tsai, M., Galan, E., Straka, R., Delgado-Lista, J., Province, M., Ruano, J., Borecki, I., Hixson, J., Garcia-Bailo, B., Perez-Jimenez, F., Ordovas, J.M. 2008. Postprandial Triglyceride Metabolism is Modified by the Presence of Genetic Variation at the Perilipin (PLIN) Locus in Two Caucasian Populations. American Journal of Clinical Nutrition. 87(3):744-752.
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Single Nucleotide Polymorphisms in ABCG5 and ABCG8 are associated with changes in cholestrol metabolism during weight loss
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Santosa, S., Demonty, I., Lichtenstein, A.H., Ordovas, J.M., Jones, P.J. 2007. Single Nucleotide Polymorphisms in ABCG5 and ABCG8 are associated with changes in cholestrol metabolism during weight loss. Journal of Lipid Research. 48(12):2607-2613.
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Are dietary preferences linked to genes?
- (Review Article)
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Ordovas, J.M., Tanaka, T. 2007. Are dietary preferences linked to genes? Future of Lipidology. 2(5):485-488. doi:10.2217/17460875.2.5.485
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A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
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Kathiresan, S., Manning, A.K., Demissie, S., D'Agostino, R.B., Surti, A., Guiducci, C., Gianniny, L., Burtt, N., Melander, O., Arnett, D.K., Peloso, G.M., Ordovas, J.M., Cupples, L.A., Orho-Melander, M. 2007. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Medical Genetics. 8:1.
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Speed-Mapping Quantitative Trait Loci Using Microarrays
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Lai, C., Leips, J., Zou, W., Roberts, J.F., Wollenberg, K.R., Parnell, L.D., Zeng, Z., Ordovas, J.M., Mckay, T.F. 2007. Speed-Mapping Quantitative Trait Loci Using Microarrays. Nature Methods. 4(10):839-841.
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Estimating interaction between genetic and environmental risk factors efficiency of sampling designs within a cohort
- (Peer Reviewed Journal)
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Bureau, A., Diallo, M.S., Ordovas, J.M., Cupples, L.A. 2008. Estimating interaction between genetic and environmental risk factors efficiency of sampling designs within a cohort. Epidemiology. 19(1):83-93.
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An apolipoprotein A-II polymorphism (-265T/C, rs5082), regulates postprandial response to a saturated fat overload in healthy men
- (Peer Reviewed Journal)
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Delgado-Lista, J., Perez-Jimenez, F., Tanaka, T., Perez-Martinez, P., Jiminez-Gomez, Y., Marin, C., Ruano, J., Parnell, L.D., Ordovas, J.M., Lopez-Miranda, J. 2007. An apolipoprotein A-II polymorphism (-265T/C, rs5082), regulates postprandial response to a saturated fat overload in healthy men. Journal of Nutrition. 137:2024-2028.
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Interleukin 1B genetic polymorphisms interact with polyunsaturated fatty acids to affect risk of the metabolic syndrome in the GOLDN Study
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Shen, J., Arnett, D.K., Peacock, J.M., Parnell, L.D., Aldi, K., Hixson, J.E., Tsai, M.Y., Kabagambe, E.K., Lai, C., Stratka, R.J., Ordovas, J.M. 2007. Interleukin 1B genetic polymorphisms interact with polyunsaturated fatty acids to affect risk of the metabolic syndrome in the GOLDN Study. Journal of Nutrition. 137(8):1846-1851.
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Ten commandments for the future of ageing research in the UK: a vision for action
- (Other)
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Franco, O., Krikwood, T.B., Powell, J.R., Catt, M., Goodwinn, J., Ordovas, J.M., Van Der Ouderaa, F. 2007. Ten commandments for the future of ageing research in the UK: a vision for action. BMC Geriatrics. 7:10.
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The -256T>C Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated with Body Mass Index and Food Intake in the Genetics of Lipid Lowering Drugs and Diet Network Study
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Corella, D., Arnett, D.K., Tsai, M.Y., Kabagambe, E.K., Peacock, J.M., Hixson, J.E., Straka, R.J., Province, M., Lai, C., Parnell, L.D., Borecki, I., Ordovas, J.M. 2007. The -256T>C Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated with Body Mass Index and Food Intake in the Genetics of Lipid Lowering Drugs and Diet Network Study. Clinical Chemistry.53:1144-1152.
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Fenofibrate Effect on Triglyceride and Postprandial Response of Apolipoprotein A5 Variants: The GOLDN Study
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Lai, C., Arnett, D.K., Straka, R.J., Tsai, M.Y., Peacock, J.M., Adiconis, X., Parnell, L.D., Hixson, J.E., Province, M.A., Ordovas, J.M. 2007. Fenofibrate Effect on Triglyceride and Postprandial Response of Apolipoprotein A5 Variants: The GOLDN Study. Arteriosclerosis Thrombo Vasc Biol. 27:1417-1425.
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Peroxisome proliferator-activated receptor alpha polymorphisms and postprandial lipemia in healthy men
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Tanaka, T., Ordovas, J.M., Delgado-Lista, J., Perez-Jimenez, F., Marin, C., Perez-Martinez, P., Gomez, P., Lopez-Miranda, J. 2007. Peroxisome proliferator-activated receptor alpha polymorphisms and postprandial lipemia in healthy men. Journal of Lipid Research. 48:1402-08.
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Nutrition in the genomics era: Cardiovascular disease risk and the Mediterranean diet
- (Review Article)
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Ordovas, J.M., Kaput, J., Corella, D. 2007. Nutrition in the genomics era: Cardiovascular disease risk and the Mediterranean diet. Molecular Nutrition and Food Research. 51(10):1293-9.
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Two independent apolipoprotein A5 haplotypes modulate postprandial lipoprotein metabolism in a healthy Caucasian population
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Moreno, R., Perez-Jimenez, F., Marin, C., Perez-Martinez, P., Gomez, P., Jimenez-Gomez, Y., Delgado-Lista, J., Moreno, J.A., Tanaka, T., Ordovas, J.M., Lopez-Miranda, J. 2007. Two independent apolipoprotein A5 haplotypes modulate postprandial lipoprotein metabolism in a healthy Caucasian population. Journal of Clinical Endocrinology and Metabolism. 92(6):2280-85.
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Nutritional Genomic Testing: What Role Will Clinical Labs Play?
- (Review Article)
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Ordovas, J.M. 2007. Nutritional Genomic Testing: What Role Will Clinical Labs Play?. Clinical Laboratory News. 33:4.
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Genetic Links between Diabetes Mellitus and Coronary Atherosclerosis
- (Review Article)
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Ordovas, J.M. 2007. Genetic Links between Diabetes Mellitus and Coronary Atherosclerosis. Current Atherosclerosis Reports. 9(3):204-210.
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Medicine, Genetics and Race: the Case of Cardiovascular Diseases
- (Other)
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Ordovas, J.M. 2007. Medicine, Genetics and Race: the Case of Cardiovascular Diseases. Personalized Medicine.4(1):1-6.
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The role of perilipin in human obesity and insulin resistance
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Tai, E.S., Ordovas, J.M. 2007. The role of perilipin in human obesity and insulin resistance. Current Opinion in Lipidology. 18(2):152-156.
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Gene-environment interaction: Introduction
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Ordovas, J.M. 2007. Gene-environment interaction: Introduction. Nutrition Metabolism and Cardiovascular Disease. 17(2):71.
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Identification of a functional polymorphism at the Adipose Fatty Acid Binding protein gene (FABP4) and demonstration of its association with cardiovascular disease: A path to follow
- (Review Article)
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Ordovas, J.M. 2007. Identification of a functional polymorphism at the Adipose Fatty Acid Binding protein gene (FABP4) and demonstration of its association with cardiovascular disease: A path to follow. Nutrition Reviews. 65(3):130-4.
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Heritability of Lipid Phenotypes among African-Americans: Jackson Heart Study
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Goosby Landry, L., Wilson, J.G., Lichtenstein, A.H., Ordovas, J.M., Tucker, K., Taylor, H.A., Destefano, A.L. 2007. Heritability of Lipid Phenotypes among African-Americans: Jackson Heart Study. Annual Conference on Cardiovascular Disease Epidemiology and Prevention. 115:e300.
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Scavenger Receptor Class B Type I (SCARB1) c.1119C>T Polymorphism Affects Postprandial Triglyceride Metabolism in Men
- (Peer Reviewed Journal)
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Tanaka, T., Delgado-Lista, J., Lopez-Miranda, J., Perez-Jimenez, F., Marin, C., Perez-Martinez, P., Gomez, P., Ordovas, J.M. 2007. Scavenger Receptor Class B Type I (SCARB1) c.1119C>T Polymorphism Affects Postprandial Triglyceride Metabolism in Men. Journal of Nutrition. 137:578-582.
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Postprandial Lipemia is Modified by the Presence of the APOB-516C/T Polymorphism in a Healthy Caucasian Population
- (Peer Reviewed Journal)
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Perez-Martinez, P., Perez-Jimenez, F., Ordovas, J.M., Moreno, J.A., Marin, C., Moreno, R., Jimenez-Gomez, Y., Paniagua, J.A., Lopez-Miranda, J. 2007. Postprandial Lipemia is Modified by the Presence of the APOB-516C/T Polymorphism in a Healthy Caucasian Population. Lipids. 42(2):143-150.
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Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping
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Lai, C., Parnell, L.D., Lyman, R.F., Ordovas, J.M., Mackay, T.F. 2006. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mechanisms of Aging and Development 128:237-249.
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Apoa5 Gene Variation Modulates the Effects of Dietary Fat Intake on Body Mass Index and Obesity Risk in the Framingham Heart Study
- (Peer Reviewed Journal)
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Corella, D., Lai, C., Demissie, S., Cupples, A., Manning, A.K., Tucker, K., Ordovas, J.M. 2007. APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. Journal of Molecular Medicine.85:119-128.
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The APOB -516C/T polymorphism is associated with differences in insulin sensitivity in healthy males during the consumption of diets with different fat content
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Perez-Martinez, P., Perez-Jimenez, F., Ordovas, J.M., Moreno, J.A., Moreno, R., Fuentes, F., Ruano, J., Gomez, P., Marin, C., Lopez-Miranda, J. 2007. The APOB -516C/T polymorphism is associated with differences in insulin sensitivity in healthy males during the consumption of diets with different fat content. British Journal of Nutrition. 97(4):622-627.
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Metabolic syndrome pathophysiology: the role of adipose tissue
- (Review Article)
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Laclaustra, M., Corella, D., Ordovas, J.M. 2007. Metabolic syndrome pathophysiology: the role of adipose tissue. Nutrition Metabolism and Cardiovascular Disease. 17(2):125-39.
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Nutrition and Diet in the Era of Genomics
- (Book/Chapter)
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Ordovas, J.M., Corella, D. 2008. Nutrition and Diet in the Era of Genomics. In: Willard, H.F. and Ginsburg, G.S, editors. Genomic and Personalized Medicine. vol. 1-2. New York, NY: Elsevier.
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Informative-Transmission Disequilibrium Test (i-TDT):Combined Linkage and Association Mapping That Includes Unaffected Offspring as Well as Affected Offspring
- (Peer Reviewed Journal)
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Guo, C.Y., Lunetta, K.L., Destefano, A.L., Ordovas, J.M., Cupples, L.A. 2006. Informative-Transmission Disequilibrium Test (i-TDT):Combined Linkage and Association Mapping That Includes Unaffected Offspring as Well as Affected Offspring. Genetic Epidemiology. 31(2):115-33.
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A direct assessment of genetic contribution to the incidence of coronary infarct in the general population Greek EPIC cohort
- (Peer Reviewed Journal)
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Yiannakouris, N., Trichopoulou, A., Benetou, V., Psaltopoulou, T., Ordovas, J.M., Trichooulos, D. 2006. A direct assessment of genetic contribution to the incidence of coronary infarct in the general population Greek EPIC cohort.
European Journal of Epidemiology. 21(12):859-867.
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Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet
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Troen, A.M., French, E.E., Roberts, J.F., Selhub, J., Ordovas, J.M., Parnell, L.D., Lai, C. 2006. Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age.29:29-39.
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Age and vitamin E-induced changes in Gene Expression Profiles of T cells
- (Peer Reviewed Journal)
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Han, S., Adolfsson, O., Lee, C., Prolla, T.A., Ordovas, J.M., Meydani, S. 2006. Age and vitamin E-induced changes in Gene Expression Profiles of T cells. Journal of Immunology. 177(12): 6052-6061.
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The effect of vitamin E supplementation at different ages on prevention of atherosclerosis and mortality in LDLR-/-mice
- (Abstract)
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Band, M., Goutis, J., Ordovas, J., Meydani, M. 2006. The effect of vitamin E supplementation at different ages on prevention of atherosclerosis and mortality in LDLR-/-mice. AGE. 28(1):23-24.
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Genetic Variation at the Perilipin Locus Is Associated with Changes in Serum Free Fatty Acids and Abdominal Fat Following Mild Weight Loss
- (Peer Reviewed Journal)
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Jang, Y., Kim, O., Lee, J., Koh, S., Chae, J., Kim, J., Park, S., Cho, H., Lee, J., Ordovas, J.M. 2006. Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss. International Journal of Obesity. 30:1601-1608.
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Nutrigenetics, plasma lipids, and cardiovascular risk
- (Review Article)
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Ordovas, J.M. 2006. Nutrigenetics, plasma lipids, and cardiovascular risk. Journal Of The American Dietetic Association. 106(7):1074-81.
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Perilipin Gene Variation Determines Higher Susceptibility to Insulin Resistance in Asian Women When Consuming a High-Saturated Fat, Low-Carbohydrate Diet
- (Peer Reviewed Journal)
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Corella, D., Qi, L., Tai, E., Deurenberg-Yap, M., Tan, C.E., Chew, S.K., Ordovas, J.M. 2006. Perilipin gene variation determines higher susceptibility to insulin resistance in asian women when consuming a high-saturated fat, low-carbohydrate diet. Diabetes Care. 29(6):1313-9.
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The Association of Snp276g>t at Adiponectin Gene with Circulating Adiponectin and Insulin Resistance in Response to Mild Weight Loss
- (Peer Reviewed Journal)
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Shin, M., Jang, Y., Koh, S., Chae, J., Kim, O., Lee, J., Ordovas, J.M., Lee, J. 2006. The association of SNP276G>T at adiponectin gene with circulating adiponectin and insulin resistance in response to mild weight loss. International Journal of Obesity. 30: 1702¿1708.
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The ABCG5 Polymorphism Contributes to Individual Responses to Dietary Cholesterol and Carotenoids in Eggs
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Herron, K.L., Mcgrane, M.M., Waters, D., Lofgren, I.E., Clark, R.M., Ordovas, J.M., Fernandez, M.L. 2006. The ABCG5 Polymorphism Contributes to Individual Responses to Dietary Cholesterol and Carotenoids in Eggs. Journal of Nutrition. 5:1161-1165.
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Dietary Intake of N-6 Fatty Acids Modulates Effect of Apolipoprotein A5 Gene on Plasma Fasting Triglycerides, Remnant Lipoprotein Concentrations, and Lipoprotein Particle Size: the Framingham Heart Study
- (Peer Reviewed Journal)
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Lai, C., Corella, D., Demissie, S., Cupples, A., Adiconis, X., Zhu, Y., Ordovas, J.M. 2006. Dietary intake of n-6 fatty acids modulates effect of apolipoprotein a5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the framingham heart study. Circulation. 113(17):2062-70.
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Nutrigenetics, Plasma Lipids and Cardiovascular Risk
- (Review Article)
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Ordovas, J.M. 2006. Nutrigenetics, plasma lipids and cardiovascular risk. Journal Of The American Dietetic Association. 106(7):1074-81; quiz 1083.
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Variants at the Apoa5 Locus, Association with Carotid Atherosclerosis, and Modification by Obesity: the Framingham Study
- (Peer Reviewed Journal)
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Elosua, R., Ordovas, J.M., Cupples, L., Lai, C., Demissie, S., Fox, C., Polak, J.F., Wolf, P.A., D'Agostino, R.A., O'Donnell, C. 2006. Variants at the apoa5 locus, association with carotid atherosclerosis, and modification by obesity: the framingham study. Journal of Lipid Research. 47(5):990-6.
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Uncoupling protein 2 promoter polymorphism -866G/A, central adiposity, and metabolic syndrome in Asians
- (Peer Reviewed Journal)
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Shen, H., Qi, L., Tai, E., Chew, S.K., Tan, C.E., Ordovas, J.M. 2006. Uncoupling protein 2 promoter polymorphism -866G/A, central adiposity, and metabolic syndrome in Asians. Obesity (Silver Spring, Md.). 14(4):656-61.
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Association between well-characterized lipoprotein-related genetic variants and carotid intimal medial thickness and stenosis: The Framingham Heart Study
- (Peer Reviewed Journal)
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Elosua, R., Cupples, L.A., Fox, C.S., Polak, J.F., D'Agostino, R.A., Wolf, P.A., O'Donnell, C.J., Ordovas, J.M. 2006. Association between well-characterized lipoprotein-related genetic variants and carotid intimal medial thickness and stenosis: The Framingham Heart Study. Atherosclerosis. 189(1):222-8.
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Nutrigenetics, Plasma Lipids and Cardiovascular Risk
- (Review Article)
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Ordovas, J.M. 2006. Nutrigenetics, plasma lipids and cardiovascular risk. Journal Of The American Dietetic Association. 106(7):1074-1081.
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Metagenomics: the Role of the Microbiome in Cardiovascular Diseases
- (Other)
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Ordovas, J.M., Mooser, V. 2006. Metagenomics: the role of the microbiome in cardiovascular diseases. Current Opinion in Lipidology. 17(2):157-61.
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Polymorphisms of ATP binding cassette G5 and G8 transporters: their effect on cholesterol metabolism after moderate weight loss in overweight and obese hyperlipidemic women
- (Abstract)
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Santosa, S., Demonty, I., Lichtenstein, A.H., Ordovas, J.M., Jones, P.J. 2006. Polymorphisms of ATP binding cassette G5 and G8 transporters: their effect on cholesterol metabolism after moderate weight loss in overweight and obese hyperlipidemic women. Federation of American Societies for Experimental Biology Conference. San Francisco, CA: April 1-5, 2006. Abstract no. 503.3.
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Long-Term Vitamin E Supplementation Reduces Atherosclerosis and Mortality in Ldlr-/-Mice
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Band, M., Goutis, J., Ordovas, J., Meydani, M. 2006. Long-term vitamin e supplementation reduces atherosclerosis and mortality in ldlr-/-mice. FASEB Letters. 20:A1316.
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Interleukin 6-174c>g Polymorphism Is Associated with Low Bone Mineral Density in Older Subjects Consuming Low Calcium
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Shen, J., Crosier, M.D., Parnell, L.D., Shea, K., Dawson-Hughes, B., Ordovas, J.M., Booth, S.L. 2006. Interleukin 6-174c>g polymorphism is associated with low bone mineral density in older subjects consuming low calcium. Experimental Biology 2006 Annual Meeting. April 1- 5, 2006. San Francisco, CA. Abstract no. 398.1.
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The Nutrition, Aging, and Memory in Elders (Name) Study: Design and Methods for a Study of Micronutrients and Cognitive Function in a Homebound Elderly Population
- (Peer Reviewed Journal)
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Scott, T.M., Peter, I., Tucker, K.L., Arsenault, L., Bergethon, P., Bhadelia, R., Buell, J., Collinsa, L., Dashe, J.F., Griffith, J., Hibberd, P., Leins, D., Liu, T., Ordovas, J.M., Patz, S., Price, L., Qui, W., Sarnak, M., Selhub, J., Smaldone, L., Wagner, C., Wang, L., Weiner, D., Yee, J., Rosenberg, I., Folstein, M. 2006. The nutrition, aging, and memory in elders (name) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. International Journal or Geriatric Psychiatry. 21(6):519-28.
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Genetics, Diet and Cardiovascular Diseases
- (Review Article)
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Corella, D., Ordovas, J.M. 2005. Genetics, diet and cardiovascular diseases. CABI International United Kingdom. Nutrition Abstracts and Reviews: Series A75(4):1N-13N. Available at http://www.nutritionandfoodsciences.org/Reviews.
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Single Nucleotide Polymorphisms That Influence Lipid Metabolism: Interaction with Dietary Factors
- (Review Article)
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Corella, D., Ordovas, J.M. 2005. Single nucleotide polymorphisms that influence lipid metabolism: interaction with dietary factors. Annual Review of Nutrition. Available online 5/2/2005 at http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.nutr.25.050304
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The Apoa1/c3/a4/a5 Gene Cluster, Lipid Metabolism and Cardiovascular Disease Risk
- (Review Article)
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Lai, C., Parnell, L.D., Ordovas, J.M. 2005. The apoa1/c3/a4/a5 gene cluster, lipid metabolism and cardiovascular disease risk. Current Opinion in Lipidology 2005, 16:153-166.
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The Metabolic Syndrome: Obesity and Diet Modulates the Expression of Its Genetic Predisposition
- (Book/Chapter)
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Ordovas, J.M., Corella, D. 2005. The metabolic syndrome: obesity and diet modulates the expression of its genetic predisposition. In Rios, M.S., Caro, J.F., Gutierrez Fuentes, J.A. The Metabolic Syndrome At the Beginning Of The XXIst Century: A Genetic And Molecular Approach. Madrid: Elsevier Health Sciences.
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Genetic Interactions with Diet Influence the Risk of Cardiovascular Disease
- (Review Article)
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Ordovas, J.M. 2006. Genetic interactions with diet influence the risk of cardiovascular disease. American Journal of Clinical Nutrition. 83(2):443s-446s.
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Supplement: Living Well to 100: Nutrition, Genetics, Inflammation (Preface)
- (Other)
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Ordovas, J.M. 2006. Supplement: living well to 100: nutrition, genetics, inflammation (preface). American Journal of Clinical Nutrition. 83(2):403S.
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Global Gene Expression Analysis of the Living Human Fetus Using Cell-Free Messenger Rna in Amniotic Fluid
- (Peer Reviewed Journal)
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Larrabee, P.B., Johnson, K.L., Lai, C., Ordovas, J.M., Cowan, J.W., Tantravahi, U., Bianchi, D.W. 2005. Global gene expression analysis of the living human fetus using cell-free messenger RNA in amniotic fluid. Journal of the American Medical Association. 16;293(7):836-42.
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Polyunsaturated Fatty Acids Interact with the Ppara-L162v Polymorphism to Affect Plasma Triglyceride and Apolipoprotein C-Iii Concentrations in the Framingham Heart Study
- (Peer Reviewed Journal)
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Tai, E.S., Corella, D., Demissie, S., Cupples, L.A., Coltell, O., Schaefer, E., Tucker, K., Ordovas, J.M. 2005. Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. Journal of Nutrition. 135:397-403.
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Intragenic Linkage Disequilibrium Structure of the Human Perilipin Gene (Plin) and Haplotype Associated with Increased Obesity Risk in a Multi-Ethnic Asian Population
- (Peer Reviewed Journal)
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Qi, L., Tai, E.S., Tan, C.E., Shen, H., Chew, S.K., Greenberg, A.S., Corella, D., Ordovas, J.M. 2005. Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype associated with increased obesity risk in a multi-ethnic Asian population. Journal of Molecular Medicine. Available at http://springerlink.com (E-Pub)
DOI: 10.1007/s00109-004-0630-4
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Effects of Chronic Ethanol Feeding on Hepatic Cell Proliferation, Erk Activation and Altered Hepatic Foci Formation in Diethylnitrosamine-Initiated Rats
- (Abstract)
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Chavez, P.R., Russell, R., Mason, J.B., Ordovas, J.M., Wang, X. 2005. Effects of chronic ethanol feeding on hepatic cell proliferation, ERK activation and altered hepatic foci formation in diethylnitrosamine-initiated rats [abstract]. Journal of Federation of American Societies for Experimental Biology. 19:A78.
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Vitamin E and Gene Expression in Immune Cells
- (Proceedings/Symposium)
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Han, S., Adolfsson, O., Lee, C., Prolla, T.A., Ordovas, J.M., Meydani, S. 2004. Vitamin E and gene expression in immune cells. In: Annals Of The New York Academy Of Sciences. Vitamin E and Health Symposium, May 22-24, 2004, Boston, Massachusetts, USA. p.96-101.
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Influence of the Apolipoprotein A5 Locus on Plasma Triglyceride, Remnant-Like Particles, and Lipoprotein Subfraction Concentrations -Implication for Cardiovascular Risk in the Framingham Heart Study
- (Peer Reviewed Journal)
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Lai, C., Demissie, S., Cupples, A., Zhu, Y., Adiconis, X., Parnell, L.D., Corella, D., Ordovas, J.M. 2004. Influence of the apolipoprotein a5 locus on plasma triglyceride, remnant-like particles, and lipoprotein subfraction concentrations -implication for cardiovascular risk in the framingham heart study. Arteriosclerosis Thrombosis and Vascular Biology. 2004; 45: 2096-2105
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Genetic Variation at the Perilipin (Plin) Locus Is Associated with Obesity-Related Phenotypes in White Women
- (Peer Reviewed Journal)
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Qi, L., Corella, D., Sorli, J.V., Portoles, O., Shen, H., Coltell, O., Godoy, D., Greenberg, A.S., Ordovas, J.M. 2004. Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women. Clinical Genetics. 66(4):299-310.
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Fish Consumption Shifts Lipoprotein Subfractions to a Less Atherogenic Pattern in Humans
- (Peer Reviewed Journal)
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Li, Z., Lamon-Fava, S., Otvos, J., Lichtenstein, A.H., Velez-Carrasco, W., Mcnamara, J.R., Ordovas, J.M., Schaefer, E. 2004. Fish consumption shifts lipoprotein subfractions to a less atherogenic pattern in humans. Journal of Nutrition. 134:1724-1728.
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A Common Polymorphism in the Methylenetetrahydrofolate Reductase (Mthfr) Gene Is Associated with Quantitative Ultrasound in Those with Low Plasma Folate
- (Peer Reviewed Journal)
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Mclean, R.R., Karasik, D., Selhub, J., Tucker, K., Ordovas, J.M., Russo, G.T., Cupples, A., Jacques, P., Kiel, D.P. 2004. A common polymorphism in the methylenetetrahydrofolate reductase (mthfr) gene is associated with quantitative ultrasound in those with low plasma folate. Journal of Bone and Mineral Research. 19:410-418.
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