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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Supplements Volume 102, Number S1, 1994
Environmental Health Perspectives Supplements  1994 Biostatistics and the Study of Toxicology

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Biostatistical issues in the design and analysis of animal carcinogenicity experiments
Portier-CJ
p. 5
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A comparison of continuous- and discrete- time three-state models for rodent tumorigenicity experiments
Lindsey-JC; Ryan-LM
p. 9
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Notes on the use of historical controls
Yoshimura-I; Matsumoto-K
p. 19
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Statistical methods for the beta-binomial model in teratology
Yamamoto-E; Yanagimoto-T
p. 25
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Multiple comparisons in long-term toxicity studies
Hothorn-L
p. 33
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Multiple comparison among groups of growth curves
Kamakura-T; Takizawa-T
p. 39
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Statistical evaluation of mutagenicity test data: recommendations of the U.K. Environmental Mutagen Society
Kirkland-DJ
p. 43
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Statistical analysis of data in mutagenicity assays: rodent micronucleus assay
Hayashi-M; Hashimoto-S; Sakamoto-Y; Hamada-C; Sofuni-T; Yoshimura-I
p. 49
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Biostatistical issues in the design and analysis of multiple or repeated genotoxicity assays
Edler-L
p. 53
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Nonparametric regression analysis of data from the Ames mutagenicity assay
Cologne-JB; Breslow-NE
p. 61
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Data management for toxicological studies
Horii-I
p. 71
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Statistical models for genetic susceptibility in toxicological and epidemiological investigations
Piegorsch-WW
p. 77
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Genetic risk assessment and specific-locus mutations in the ad-3 region of Neurospora crassa
de-Serres-FJ
p. 83
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Some comments on potency measures in mutagenicity research
Margolin-BH; Kim-BS; Smith-MG; Fetterman-BA; Piegorsch-WW; Zeiger-E
p. 91
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Statistical issues on the no-observed-adverse-effect level in categorical response
Yanagawa-T; Kikuchi-Y; Brown-KG
p. 95
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Physiologically based pharmacokinetics and cancer risk assessment
Andersen-ME; Krishnan-K
p. 103
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Nonlinearity of dose-response functions for carcinogenicity
Hoel-DG; Portier-CJ
p. 109
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Statistical characterization of negative control data in the Ames Salmonella/microsome test
Hamada-C; Wada-T; Sakamoto-Y
p. 115
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Biostatistical analysis of the micronucleus mutagenicity assay based on the assumption of a mixing distribution
Hothorn-L
p. 121
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Predicting carcinogenicity by using batteries of dependent short-term tests
Kim-BS; Margolin-BH
p. 127
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A new model of shouldered survival curves
Kumazawa-S
p. 131
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Chlorinated and brominated dioxins and dibenzofurans in human tissue following exposure
Schecter A; Ryan-JJ; Masuda-Y; Brandt-Rauf-P; Constable-J; Hoang-DC; Le-CD; Hoang-TQ; Nguyen-TN; Pham-HP
p. 135
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Polychlorinated biphenyl levels in the tissues of exposed and nonexposed humans
Schecter A; Stanley-J; Boggess-K; Masuda-Y; Mes-J; Wolff-M; Furst-P; Furst-C; Wilson-Yang-K; Chisholm-B
p. 149
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Chlorinated dioxins and dibenzofurans in human tissue from general populations: a selective review
Schecter A; Furst-P; Furst-C; Papke-O; Ball-M; Ryan-JJ; Hoang-DC; Le-CD; Hoang-TQ; Cuong-HQ; et-al
p. 159
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PCDD and PCDF exposure and levels in humans in Germany
Beck-H; Dross A; Mathar-W
p. 173
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Human milk as a bioindicator for body burden of PCDDs, PCDFs, organochlorine pesticides, and PCBs
Furst-P; Furst-C; Wilmers-K
p. 187
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Levels of non-ortho-substituted (coplanar), mono- and di-ortho-substituted polychlorinated biphenyls, dibenzo-p-dioxins, and dibenzofurans in human serum and adipose tissue
Patterson-DG Jr; Todd-GD; Turner-WE; Maggio-V; Alexander-LR; Needham-LL
p. 195
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Exposure of remote maritime populations to coplanar PCBs
Dewailly-E; Ryan-JJ; Laliberte-C; Bruneau-S; Weber-JP; Gingras-S; Carrier-G
p. 205
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Chlorinated organic contaminants in breast milk of New Zealand women
Bates-MN; Hannah-DJ; Buckland-SJ; Taucher-JA; van-Maanen-T
p. 211
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Assessment of human exposure to chemicals from Superfund sites
Kamrin-MA; Fischer-LJ; Suk-WA; Fouts-JR; Pellizzari-E; Thornton-K
p. 221
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Application of molecular biomarkers in epidemiology
Smith-MT; Suk-WA
p. 229
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Health effects of combustion by-products
Sarofim AF; Suk-WA
p. 237
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Biodegradation of hazardous wastes
Aust-SD; Bourquin A; Loper-JC; Salanitro-JP; Suk-WA; Tiedje-J
p. 245
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Dose-response relationship in multistage carcinogenesis: promoters
Kitchin-KT; Brown-JL; Setzer-RW
p. 255
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Polybrominated dibenzo-p-dioxins and dibenzofurans: literature review and health assessment
Mennear-JH; Lee-CC
p. 265
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Risk assessment of nickel carcinogenicity and occupational lung cancer
Shen-HM; Zhang-QF
p. 275
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Bacterial mutagenicity of pyrolysis tars produced from chloro-organic fuels
Mulholland-JA; Sarofim AF; Longwell-JP; Lafleur AL; Thilly-WG
p. 283
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