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| Human beings are a hardy species. Despite war, famine, disease, and contraception, the global human population continues to grow, although in ever-changing ways. This month's Focus article (p. A598) looks at global population dynamics--how much we're growing, where we're living, how many resources we're consuming--and where these trends are likely to lead us in the future.
image credit: Betty Press/Panos Pictures Purchase This Issue | |
Perspectives
Director's Perspective
p. A 578
Correspondence
p. A 580
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Environews
Forum
p. A 588
NIEHS News
p. A 592
Focus
p. A 598
Spheres of Influence
p. A 606
Innovations
p. A 610
Science Selections
p. A 614
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Commentaries & Reviews
RISK ASSESSMENT | The NAS Perchlorate Review: Questions Remain about the Perchlorate RfD
Gary Ginsberg and Deborah Rice
p. 1117 [ Abstract ] [ Full ] [ PDF ]
TOXICOLOGY | Methylmercury Contamination of Laboratory Animal Diets
Bernard Weiss, Sander Stern, Elsa Cernichiari, and Robert Gelein
p. 1120 [ Abstract ] [ Full ] [ PDF ]
REMEDIATION | Arsenic: A Roadblock to Potential Animal Waste Management Solutions
Keeve E. Nachman, Jay P. Graham, Lance B. Price, and Ellen K. Silbergeld
p. 1123 [ Abstract ] [ Full ] [ PDF ]
CANCER | Assessing Susceptibility from Early-Life Exposure to Carcinogens
Hugh A. Barton, V. James Cogliano, Lynn Flowers, Larry Valcovic, R. Woodrow Setzer, and Tracey J. Woodruff
p. 1125 [ Abstract ] [ Full ] [ PDF ]
Research
CANCER | Acquisition of Androgen Independence by Human Prostate Epithelial Cells during Arsenic-Induced Malignant Transformation
Lamia Benbrahim-Tallaa, Mukta M. Webber, and Michael P. Waalkes
Also see Science Selections, p. A614
p. 1134 [ Abstract ] [ Full ] [ PDF ]
RESPIRATORY DISEASE | Fine Particulate Matter National Ambient Air Quality Standards: Public Health Impact on Populations in the Northeastern United States
Philip R.S. Johnson and John J. Graham
p. 1140 [ Abstract ] [ Full ] [ PDF ]
RISK ASSESSMENT | Using Moving Total Mortality Counts to Obtain Improved Estimates for the Effect of Air Pollution on Mortality
Steven Roberts
p. 1148 [ Abstract ] [ Full ] [ PDF ]
RISK CHARACTERIZATION | Dietary Intake and Arsenic Methylation in a U.S. Population
Craig Steinmaus, Kenichi Carrigan, Dave Kalman, Raja Atallah, Yan Yuan, and Allan H. Smith
p. 1153 [ Abstract ] [ Full ] [ PDF ]
ENDOCRINE | Pesticide Exposure Alters Follicle-Stimulating Hormone Levels in Mexican Agricultural Workers
Rogelio Recio, Guadalupe Ocampo-Gómez, Javier Morán-Martínez, Victor Borja-Aburto, Malaquías López-Cervantes, Marisela Uribe, Luisa Torres-Sánchez, and Mariano E. Cebrián
p. 1160 [ Abstract ] [ Full ] [ PDF ]
TOXICOGENOMICS | Design of a Microsphere-Based High-Throughput Gene Expression Assay to Determine Estrogenic Potential
Jorge M. Naciff, Brian D. Richardson, Kerry G. Oliver, M. Lynn Jump, Suzanne M. Torontali, Kenton D. Juhlin, Gregory J. Carr, Jennifer R. Paine, Jay P. Tiesman, and George P. Daston
p. 1164 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT | Microwaves from GSM Mobile Telephones Affect 53BP1 and -H2AX Foci in Human Lymphocytes from Hypersensitive and Healthy Persons
Eva Markovà, Lena Hillert, Lars Malmgren, Bertil R. R. Persson, and Igor Y. Belyaev
p. 1172 [ Abstract ] [ Full ] [ PDF ]
MIXTURES | Physiologic and Symptomatic Responses to Low-Level Substances in Individuals with and without Chemical Sensitivities: A Randomized Controlled Blinded Pilot Booth Study
Michel R. Joffres, Tara Sampalli, and Roy A. Fox
p. 1178 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT | Correlating Agricultural Use of Organophosphates with Outdoor Air Concentrations: A Particular Concern for Children
Martha Harnly, Robert McLaughlin, Asa Bradman, Meredith Anderson, and Robert Gunier
p. 1184 [ Abstract ] [ Full ] [ PDF ]
RISK CHARACTERIZATION | Testing the Dose-Response Specification in Epidemiology: Public Health and Policy Consequences for Lead
Stephen J. Rothenberg and Jesse C. Rothenberg
p. 1190 [ Abstract ] [ Full ] [ PDF ]
ANALYTICAL CHEMISTRY | The Development and Use of an Innovative Laboratory Method for Measuring Arsenic in Drinking Water from Western Bangladesh
Seth H. Frisbie, Erika J. Mitchell, Ahmad Zaki Yusuf, Mohammad Yusuf Siddiq, Raul E. Sanchez, Richard Ortega, Donald M. Maynard, and Bibudhendra Sarkar
p. 1196 [ Abstract ] [ Full ] [ PDF ]
CANCER | Meeting Report: Summary of IARC Monographs on Formaldehyde, 2-Butoxyethanol, and 1-tert-Butoxy-2-Propanol
Vincent James Cogliano, Yann Grosse, Robert A. Baan, Kurt Straif, Marie Béatrice Secretan, Fatiha El Ghissassi, and the Working Group for Volume 88
p. 1205 [ Abstract ] [ Full ] [ PDF ]
Environmental Medicine
CANCER | -Aminolevulinic Acid Dehydratase Polymorphism and Risk of Brain Tumors in Adults
Preetha Rajaraman, Brian S. Schwartz, Nathaniel Rothman, Meredith Yeager, Howard A. Fine, William R. Shapiro, Robert G. Selker, Peter M. Black, and Peter D. Inskip
Also see Science Selections, p. A616
p. 1209 [ Abstract ] [ Full ] [ PDF ]
Children's Health
FETAL DEVELOPMENT | Local Variations in CO and Particulate Air Pollution and Adverse Birth Outcomes in Los Angeles County, California, USA
Michelle Wilhelm and Beate Ritz
Also see Science Selections, p. A615
p. 1212 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT | Use of Di(2-ethylhexyl) Phthalate-Containing Medical Products and Urinary Levels of Mono(2-ethylhexyl) Phthalate in Neonatal Intensive Care Unit Infants
Ronald Green, Russ Hauser, Antonia M. Calafat, Jennifer Weuve, Ted Schettler, Steven Ringer, Kenneth Huttner, and Howard Hu
Also see Science Selections, p. A614
p. 1222 [ Abstract ] [ Full ] [ PDF ]
MUTAGENESIS | Baseline Micronuclei Frequency in Children: Estimates from Meta- and Pooled Analyses
Monica Neri, Marcello Ceppi, Lisbeth E. Knudsen, Domenico Franco Merlo, Roberto Barale, Riccardo Puntoni, and Stefano Bonassi
p. 1226 [ Abstract ] [ Full ] [ PDF ]
Mini-Monograph
NEURODEGENERATIVE DISEASE | Early Environmental Origins of Neurodegenerative Disease in Later Life
Philip J. Landrigan, Babasaheb Sonawane, Robert N. Butler, Leonardo Trasande, Richard Callan, and Daniel Droller
p. 1230 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | The Role of Early Life Environmental Risk Factors in Parkinson Disease: What Is the Evidence?
Giancarlo Logroscino
p. 1234 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | Fetal Environment and Schizophrenia
Mark G.A. Opler and Ezra S. Susser
p. 1239 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | Pharmacokinetic and Pharmacodynamic Factors That Can Affect Sensitivity to Neurotoxic Sequelae in Elderly Individuals
Gary Ginsberg, Dale Hattis, Abel Russ, and Babasaheb Sonawane
p. 1243 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | Neurodegenerative Diseases: An Overview of Environmental Risk Factors
Rebecca C. Brown, Alan H. Lockwood, and Babasaheb R. Sonawane
p. 1250 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | Aging and the Environment: A Research Framework
Andrew M. Geller and Harold Zenick
p. 1257 [ Abstract ] [ Full ] [ PDF ]
NEURODEGENERATIVE DISEASE | Developmental Pesticide Models of the Parkinson Disease Phenotype
Deborah A. Cory-Slechta, Mona Thiruchelvam, Brian K. Barlow, and Eric K. Richfield
p. 1263 [ Abstract ] [ Full ] [ PDF ]
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