Project Number: 1265-31000-098-08
Project Type: Reimbursable

Start Date: Jan 01, 2008
End Date: Mar 31, 2010

Objective:
Identify genome signatures of artificial selection by genotyping and analyzing at least 48,000 SNPs covering all the 29 bovine autosomes and the X-chromosome on 1008 cows from the control line, selection line, and the mixed and elite contemporary Holstein lines. Then to identify those SNP markers associated with daughter pregnancy rate, somatic cell Scores, productive life, and milk production traits by genome-wide association analysis of additive and non-additive effects.

Approach:
The two objectives of detecting signatures of selection and genome-wide association between SNP markers and economically important dairy traits will be achieved by genotyping and analyzing at least 48,000 SNPs on 1008 Holsteins cows from four lines. These four lines were chosen and defined to maximize general genome differences and genetic differences for economically important traits among Holstein cows in this study.