Keywords: chronic stable angina, antianginal, ranolazine, diabetes mellitus, glycated hemoglobin
|
Copyright © 2008 Patel and Arora, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. Utility of ranolazine in chronic stable angina patients Correspondence: Rohit R Arora Department of Cardiology, Chicago Medical School, North Chicago VA Medical Centre-133B, 3001 Green Bay Road, North Chicago, IL-60064, USA Tel +1 224 610 4503 Fax +1 224 610 3878 Email
rohit.arora/at/va.gov | ||||
Abstract Chronic stable angina is a debilitating illness affecting at least 6.6 million US residents. Despite being optimally treated by pharmacotherapy and revascularization up to 26% of patients still experience angina. Diabetes mellitus is a common co-morbid condition in angina patients. Several new investigational medications are being tested for chronic angina. Advances in understanding of myocardial ischemia have prompted evaluation of a number of new antianginal strategies. In this review we discuss the utility of ranolazine, a recently approved novel antianginal agent and its efficacy in the diabetic patient population. In addition to its antianginal action in diabetic patients with chronic angina, ranolazine may have favorable effects on glycated hemoglobin levels. Keywords: chronic stable angina, antianginal, ranolazine, diabetes mellitus, glycated hemoglobin | ||||