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Volume 10;  2009
Commentaries
Readers as research detectives
Peter C Gøtzsche
Trials. 2009; 10: 2. Published online 2009 January 7. doi: 10.1186/1745-6215-10-2.
PMCID: PMC2632628
The clinically-integrated randomized trial: proposed novel method for conducting large trials at low cost
Andrew J Vickers and Peter T Scardino
Trials. 2009; 10: 14. Published online 2009 March 5. doi: 10.1186/1745-6215-10-14.
PMCID: PMC2656491
Editorial
Towards agreement on best practice for publishing raw clinical trial data
Iain Hrynaszkiewicz and Douglas G Altman
Trials. 2009; 10: 17. Published online 2009 March 18. doi: 10.1186/1745-6215-10-17.
PMCID: PMC2662833
Methodology
No short-cut in assessing trial quality: a case study
Karim F Hirji
Trials. 2009; 10: 1. Published online 2009 January 7. doi: 10.1186/1745-6215-10-1.
PMCID: PMC2636799
How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design – a reanalysis of 4 trials
FM-S Barthel, MKB Parmar, and P Royston
Trials. 2009; 10: 21. Published online 2009 April 17. doi: 10.1186/1745-6215-10-21.
PMCID: PMC2680399
Research
Metformin treatment in diabetes and heart failure: when academic equipoise meets clinical reality
Dean T Eurich, Ross T Tsuyuki, Sumit R Majumdar, Finlay A McAlister, Richard Lewanczuk, Marcelo C Shibata, and Jeffrey A Johnson
Trials. 2009; 10: 12. Published online 2009 February 9. doi: 10.1186/1745-6215-10-12.
PMCID: PMC2644685
Paying clinicians to join clinical trials: a review of guidelines and interview study of trialists
James Raftery, Christine Kerr, Sheila Hawker, and John Powell
Trials. 2009; 10: 15. Published online 2009 March 10. doi: 10.1186/1745-6215-10-15.
PMCID: PMC2657143
Review
The challenges faced in the design, conduct and analysis of surgical randomised controlled trials
Jonathan A Cook
Trials. 2009; 10: 9. Published online 2009 February 6. doi: 10.1186/1745-6215-10-9.
PMCID: PMC2654883
Study Protocol
Acupuncture, or non-directive counselling versus usual care for the treatment of depression: a pilot study
Sylvia Schroer and Hugh MacPherson
Trials. 2009; 10: 3. Published online 2009 January 9. doi: 10.1186/1745-6215-10-3.
PMCID: PMC2636800
The impact of iron supplementation efficiency in female blood donors with a decreased ferritin level and no anaemia. Rationale and design of a randomised controlled trial: a study protocol
Baptiste Pedrazzini, Sophie Waldvogel, Jacques Cornuz, Paul Vaucher, Raphael Bize, Jean-Daniel Tissot, Alain Pecoud, and Bernard Favrat
Trials. 2009; 10: 4. Published online 2009 January 16. doi: 10.1186/1745-6215-10-4.
PMCID: PMC2637271
Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II
Fereidoun Azizi, Arash Ghanbarian, Amir Abbas Momenan, Farzad Hadaegh, Parvin Mirmiran, Mehdi Hedayati, Yadollah Mehrabi, Saleh Zahedi-Asl, and the Tehran Lipid and Glucose Study Group
Trials. 2009; 10: 5. Published online 2009 January 25. doi: 10.1186/1745-6215-10-5.
PMCID: PMC2656492
A randomised controlled trial of the Neuro Emotional Technique (NET) for childhood Attention Deficit Hyperactivity Disorder (ADHD): a protocol
Fay Karpouzis, Henry Pollard, and Rod Bonello
Trials. 2009; 10: 6. Published online 2009 January 27. doi: 10.1186/1745-6215-10-6.
PMCID: PMC2646715
A randomized prospective trial of the postoperative quality of life between laparoscopic uterine artery ligation and laparoscopy-assisted vaginal hysterectomy for the treatment of symptomatic uterine fibroids: clinical trial design
Hee Seung Kim, Jae Weon Kim, Mi-Kyung Kim, Hyun Hoon Chung, Taek Sang Lee, Yong-Tark Jeon, Yong Beom Kim, Hye Won Jeon, Young Ho Yun, Noh Hyun Park, Yong Sang Song, and Soon-Beom Kang
Trials. 2009; 10: 8. Published online 2009 January 29. doi: 10.1186/1745-6215-10-8.
PMCID: PMC2645389
Study protocol: Couples Partnering for Lipid Enhancing Strategies (CouPLES) – a randomized, controlled trial
Corrine I Voils, William S Yancy, Jr, Stacey Kovac, Cynthia J Coffman, Morris Weinberger, Eugene Z Oddone, Amy Jeffreys, Santanu Datta, and Hayden B Bosworth
Trials. 2009; 10: 10. Published online 2009 February 6. doi: 10.1186/1745-6215-10-10.
PMCID: PMC2652451
Exercise therapy, manual therapy, or both, for osteoarthritis of the hip or knee: a factorial randomised controlled trial protocol
J Haxby Abbott, M Clare Robertson, Joanne E McKenzie, G David Baxter, Jean-Claude Theis, A John Campbell, and the MOA Trial team
Trials. 2009; 10: 11. Published online 2009 February 8. doi: 10.1186/1745-6215-10-11.
PMCID: PMC2644684
Hypertension Improvement Project (HIP): study protocol and implementation challenges
Rowena J Dolor, William S Yancy, Jr, William F Owen, David B Matchar, Gregory P Samsa, Kathryn I Pollak, Pao-Hwa Lin, Jamy D Ard, Maxwell Prempeh, Heather L McGuire, Bryan C Batch, William Fan, and Laura P Svetkey
Trials. 2009; 10: 13. Published online 2009 February 26. doi: 10.1186/1745-6215-10-13.
PMCID: PMC2654882
New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6
Rafael Garcia-Lopez, Emilio Perea-Milla, Cesar Ruiz Garcia, Francisco Rivas-Ruiz, Julio Romero-Gonzalez, Jose L Moreno, Vicente Faus, Guadalupe del Castillo Aguas, and Juan C Ramos Diaz
Trials. 2009; 10: 16. Published online 2009 March 10. doi: 10.1186/1745-6215-10-16.
PMCID: PMC2660319
The second Symptom Management Research Trial in Oncology (SMaRT Oncology-2): a randomised trial to determine the effectiveness and cost-effectiveness of adding a complex intervention for major depressive disorder to usual care for cancer patients
Jane Walker, Jim Cassidy, Michael Sharpe, and the SMaRT Oncology-2 Trialists*
Trials. 2009; 10: 18. Published online 2009 March 30. doi: 10.1186/1745-6215-10-18.
PMCID: PMC2669069
Anaesthesiological strategies in elective craniotomy: randomized, equivalence, open trial – The NeuroMorfeo trial
Giuseppe Citerio, Maria Grazia Franzosi, Roberto Latini, Serge Masson, Simona Barlera, Stefano Guzzetti, and Antonio Pesenti
Trials. 2009; 10: 19. Published online 2009 April 6. doi: 10.1186/1745-6215-10-19.
PMCID: PMC2673222
Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD)
Baiba Hedegaard Hansen, Jamal Abed Hanash, Alice Rasmussen, Jørgen Fischer Hansen, and Morten Birket-Smith
Trials. 2009; 10: 20. Published online 2009 April 7. doi: 10.1186/1745-6215-10-20.
PMCID: PMC2674039
The design and protocol of acupuncture for migraine prophylaxis: A multicenter randomized controlled trial
Yan Zhang, Linpeng Wang, Huilin Liu, Nan Li, Jingdao Li, and Jinghong Yi
Trials. 2009; 10: 25. Published online 2009 April 24. doi: 10.1186/1745-6215-10-25.
PMCID: PMC2680846
Protocol for the Proactive Or Reactive Telephone Smoking CeSsation Support (PORTSSS) trial
Tim Coleman, Andy McEwen, Linda Bauld, Janet Ferguson, Paula Lorgelly, and Sarah Lewis
Trials. 2009; 10: 26. Published online 2009 April 28. doi: 10.1186/1745-6215-10-26.
PMCID: PMC2679731
Correction
A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics
Caroline Laurence, Angela Gialamas, Lisa Yelland, Tanya Bubner, Philip Ryan, Kristyn Willson, Briony Glastonbury, Janice Gill, Mark Shephard, Justin Beilby, and for members of the PoCT Trial Management Committee
Trials. 2009; 10: 7. Published online 2009 January 28. doi: 10.1186/1745-6215-10-7.
PMCID: PMC2651873
Corrects: Caroline Laurence, et al. A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics. Trials. 2008; 9: 50.
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