| |
| October 9th, Morning Sessions |
|
| INTRODUCTIONS |
| 8:30 |
Robert Wiltrout (Director, Center for Cancer Research, NCI) |
| 8:40 |
John Niederhuber (Director, NCI) |
| 8:50 |
Giorgio Trinchieri (Director, Cancer and Inflammation Program,
CCR/NCI) |
| |
|
| OPENING TALK (Chair G.
Trinchieri) |
| 9:00 |
Hans Schreiber, University of Chicago, IL
Cancer
Cells, Stroma and CD8+ T Cells: Eradication, Equilibrium, or Escape |
| |
| SESSION 1-INNATE RESISTANCE AND CANCER (Chair
H. Young) |
| 9:30 |
Douglas Golenbock, U. Massachusetts’ Medical Center, Worcester,
MA
Mechanisms
of Toll-like Receptor Activation and Function |
| 9:55 |
David Segal, NCI
The
Interaction of TLR3 with dsRNA |
| 10:20 |
Dennis Klinman, NCI
Synthetic
Oligodeoxynucleotides as Modulators of Inflammation |
| 10:45 |
Coffee break |
| 11:15 |
Mark Smyth, Peter MacCallum Cancer Centre, East Melbourne, Australia
Cancer
Immune Surveillance: a Balancing Act |
| 11:40 |
Lalage Wakefield, NCI
TGF-beta
Subverts CD8+ cells into Directly Promoting Tumor Growth Through
an IL-17 Mediated Mechanism |
| 12:05 |
Masaki Terabe, NCI
Two
Subsets of NKT cells Form a New Immunoregulatory Axis in Tumor Immunity |
| |
|
12:30-2:00 Lunch
break |
| |
|
October 9th, Afternoon Sessions |
|
SESSION 2-COLON AND PROSTATE CANCERS (Chair
S. Durum) |
| 2:00 |
Peter Murray, St. Jude Hospital, Memphis, TN
Arginine
Metabolism in Chronic Inflammation |
| 2:25 |
Andrew Dannenberg, New York Presbyterian Hospital-Cornell,
New York, NY
Prostaglandins,
Inflammatory Bowel Disease and Colon Cancer:
What is Nature
Teaching Us? |
| 2:50 |
Curtis Harris, NCI
Interactions
of Cytokines, Free Radicals and MicroRNAs in Inflammation-Associated
Cancer |
| 3:15 |
Wolf Herve Fridman, INSERM U255 and Hôpital Européen
Georges-Pompidou, Paris, France
The
In Situ Immune Reaction, a Major Player in Human Cancer |
| 3:40 |
Coffee break |
| 4:20 |
William Nelson,
Johns Hopkins University School of Medicine, Baltimore, MD
Prostate
Cancer Epigenetics and Inflammation |
| 4:55 |
Arthur Hurwitz, NCI
Understanding
T Cell Responses to Prostate Cancer in Mice |
| |
|
October 10, 2007, Morning
Session |
|
OPENING TALK (Chair R. Wiltrout) |
| 8:30 |
Drew Pardoll, Johns Hopkins University School of Medicine, Baltimore,
MD
Immune
Mechanisms for Tumorigenesis by Chronic Infections |
| |
|
SESSION 3-SKIN CANCERS (Chair J. Oppenheim) |
| 9:00 |
Margareta Mueller, German Cancer Research Center, Heidelberg,
Germany
Inflammation,
Angiogenesis and Tumor Invasion |
| 9:25 |
Stuart Yuspa, NCI
Inflammatory
Mediators of Cutaneous Carcinogenesis: Evidence for an Autocrine
Mechanism of Action |
| 9:50 |
Sam Hwang, NCI
Chemokine
Receptors in Melanoma Resistance to Host Immunity |
| 10:15 |
Francesco Marincola, NIH Clinical Center
Models for Transcriptional Profiling of Tumor Rejection
in Humans |
| 10:40 |
Coffee break |
| |
|
SESSION 4-CANCERS WITH AN INFECTIOUS PATHOGENESIS
(Chair
C. Mackall) |
| 11:10 |
Snorri Thorgeirsson, NCI
Inflammation
and Pathogenesis of Liver Cancer |
| 11:35 |
Xin Wei Wang, NCI
Inflammatory
Architects of Metastatic Hepatocellular Carcinoma |
| 12:00 |
Douglas Lowy, NCI
HPV
Vaccines and Other Interventions to Prevent HPV Infection and Cervical
Cancer |
| 12:25 |
Giovanna Tosato, NCI
A
Role for Cytokines and Chemokines in KHSV-Associated Malignancies |
| |
|
12:50-2:10 Lunch
Break |
| |
|
October 10, 2007, Afternoon
Session |
|
SESSION 5-THE INFLAMMATORY TUMOR MICRO-ENVIRONMENT (Chair
J. Berzofsky) |
| 2:10 |
Thomas Wynn, NIAID
Regulation
of Chronic Inflammation and Fibrosis by IL-13, NOS2, and Arginase-1 |
| 2:35 |
Vincenzo Bronte, Padua University, Italy
Altered
Macrophage Differentiation and Immune Dysfunction in Tumor Development |
| 3:00 |
Suzanne Ostrand-Rosenberg, University of Maryland, Baltimore
MD
Inflammation,
Immune Suppression and Tumor Progression |
| 3:25 |
Coffee break |
| 3:55 |
Hua Yu, City of Hope National Medical Center, Duarte, CA
Role
of Stat3 in Cancer and Inflammation |
| 4:20 |
Frances Balkwill, Institute of Cancer and Queen Mary's School
of Medicine and Dentistry, London, GB
The
Inflammatory Cytokine TNF-alpha as a Target for Cancer Treatment |
| 4:55 |
Daniel McVicar, NCI
Regulation
of Inflammation by the TREM Gene Cluster |
