![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) |
|
![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif)
zibotentan An orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif)
Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) | ZD4054 | | ![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure names: | ![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) | - 3-pyridinesulfonamide, N-(3-methoxy-5-methyl-2-pyrazinyl)-2-[4-(1,3,4-oxadiazol-2- yl)phenyl]-
- N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pridine-3- sulfonamide
| | ![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) |
Previous: | Zemplar, Zenapax, Zerit, Zevalin, Zevalin | Next: | ziconotide, zidovudine, zileuton, zinc sulfate, Zinecard |
|
![](https://webarchive.library.unt.edu/eot2008/20090513100829im_/http://www.cancer.gov/images/spacer.gif) |