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Past Announcements:
• Effective 2-1-08, B6CBAF1/Cr (01B13) is unavailable.
• Effective 2-15-08, CD2F1/Cr (01B11) is unavailable.
Reduction in NCI Maintained Strains/Stocks
Start of NCI BALB/cAnN colony from NIH
• CD2F1/Cr mice available
C3H/HeJCr 3/05 update
C3H/HeJCr 4/05 update
New BALB/c Substrain
Nomenclature - Inbred Mice

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Animal Production Program

  01C71 C57BL/10ScN
(C57BL/10, B10, C57 / 10ScBs)

Origin: To N 1953 from Snell at F35. See C57BL/KaLwn – 15, but from Russell to Scott at F26, then to Snell.
Genetics:

a, B, C
Intense black
Genes:

Car-2a, Ce-2a, Cs-1g, Es-1a, Es-3a, Es-10a, Gpd-1a, Gpi-1b, Hbbs, Idh-1a, Lvc, Mod-1b, Mup-1b, Pep-3a, Pgm-1a, Trfb
Hc1, H-2Db, H-2Kb, Lyt-1b, Lyt-2b, Lyt-3b, Thy-1b, Tlab.

   
Diseases
    Neoplastic (Spontaneous):
 
  • Very low mammary tumor incidence. (680)
   
    Neoplastic (Induced):
 
  • In comparison with other inbred strains, C57BL/10 is resistant to Gross, Bittner, Friend S and B viruses, and relatively resistant to Tennant virus. (370)
   
    Non-Neoplastic (Induced):
 
  • Relatively resistant to induction of cleft palate by cortisone. (067)
   
Other Characteristics
    Immunologic:
 
  • Macrophages from BDG-infected, LPS-unresponsive C57BL/10ScCR mice were not tumoricidal in vitro, but cells from BCG-infected LPS-responsive C57BL/10Sn from Jackson lab were. (608)
  • High interferon serum levels after induction by Newcastle disease virus. (696)
   
    Physiologic:
 
  • High resting plasma steroid levels, and responds to acute stress by prolonged elevation. (398)
 
    Behavioral:
 
  • High preference for ethanol and for morphine presented in a saccharine vehicle. (794)